Protein Alignment eve and HOXA1

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005513.2
• Gene: HOXA1 / 3198
• HGNCID: 5099
• Length: 335
• Species: Homo sapiens
• Alignment Length: 149
• Identity: 49/149 - (32%)
• Similarity: 67/149 - (44%)
• Gaps: 29/149 - (19%)

  Fly     9 MESHHAHHD-------ASP--------VDQKPLVV----DLLATQYGKPQTPPPSPNECLSSPDN 54
            |..||.||.       .||        .:.:.|.:    :.|:..:...|....||....|||..
Human   139 MVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQ 203

  Fly    55 SLNGSRGSEIPADP-SVRRY---------RTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNL 109
            :.:..:....|... .|..|         ||.||..||..|||||:...|::|.||.|:||.|.|
Human   204 TFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQL 268

  Fly   110 PESTIKVWFQNRRMKDKRQ 128
            .|:.:|:||||||||.|::
Human   269 NETQVKIWFQNRRMKQKKR 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	31/64 (48%)
HOXA1	NP_005513.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..80
		Interaction with OGT. /evidence=ECO:0000250|UniProtKB:P09022	75..203		15/63 (24%)
		COG5576	176..>286	CDD:227863	40/109 (37%)
		Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	30/52 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..335		4/7 (57%)