Protein Alignment eve and HLX

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 73/307 - (23%)
• Similarity: 100/307 - (32%)
• Gaps: 96/307 - (31%)

  Fly    50 SSPDNSLNGSRGSEIPA-------DPSVRRY-------RTAFTRDQLGRLEKEFYKENYVSRPRR 100
            |:|.||:........|.       |...:.|       |..|:..|...|||.|..:.||::|.|
Human   242 SNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDR 306

  Fly   101 CELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYA 165
            .:|||.|.|.::.:||||||||||         |.    :|..|.|.......|..        .
Human   307 KQLAAMLGLTDAQVKVWFQNRRMK---------WR----HSKEAQAQKDKDKEAGE--------K 350

  Fly   166 PAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAP 230
            |:..|.||.......:|..:.|..........::.|..........|....::.|....|...|
Human   351 PSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGA- 414

  Fly   231 PHPAGPHMHHPHMMGSSATGSSYSAGAAG----------LLGALPSATCYTGLGVG-----VPKT 280
                        ::.:|:.||..|:|..|          |..:..||.|.:.||.|     :|.|
Human   415 ------------LITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPAT 467

  Fly   281 QTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSAPSVPAPA 327
            |                                 |.|.|||..|.||
Human   468 Q---------------------------------PTASSAPKSPEPA 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	27/62 (44%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173
		Homeodomain	273..333	CDD:459649	27/72 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		40/209 (19%)