Protein Alignment eve and Nkx1-1

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_234082.6
• Gene: Nkx1-1 / 298981
• RGDID: 1564874
• Length: 443
• Species: Rattus norvegicus
• Alignment Length: 252
• Identity: 70/252 - (27%)
• Similarity: 100/252 - (39%)
• Gaps: 59/252 - (23%)

  Fly    14 AHHDASPVDQKPLVVDLLATQYGKPQTPP--PSPNECLSSPDNSLNGSRGSEIPADP-------- 68
            |..:|||||:        |...|.....|  |.|....:...|:.:..:|:.:...|
  Rat   229 AEVEASPVDE--------AAAPGPRGNSPGAPGPPVTAAGAGNAGSTPQGAAVATKPKRKRTGSD 285

  Fly    69 ----SVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQR 129
                ..||.|||||.:||..||.:|....|:|...|..||..|:|.|:.:|:||||||.|.|:|
  Rat   286 SKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ- 349

  Fly   130 IAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGMP 194
                        :|....|   |.....|.|.|...|.|....      ..:|:..:  ||||.|
  Rat   350 ------------NPGADTS---APTGGGGGPGPGAGPGAGLPG------GLSPLSPS--PPMGAP 391

  Fly   195 QMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHPHMMGSSATGS 251
                :.:.|.:|:..| ||.|        :......|..:.|.:..|.::||...|:
  Rat   392 ----LALHGPAGYPAH-SPGG--------LVCAAQLPFLSSPAVLSPFVLGSQTYGA 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	28/55 (51%)
Nkx1-1	XP_234082.6	Homeodomain	292..348	CDD:459649	28/55 (51%)