Protein Alignment eve and VAX2

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_036608.1
• Gene: VAX2 / 25806
• HGNCID: 12661
• Length: 290
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 69/242 - (28%)
• Similarity: 97/242 - (40%)
• Gaps: 52/242 - (21%)

  Fly    44 SPNECLSSPDNSLNGSR--GSEIPADPS--------------------------------VRRYR 74
            ||.|...:..:|..|||  |::....|.                                .:|.|
Human    42 SPTEVAGTSASSPAGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTR 106

  Fly    75 TAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAV 139
            |:||.:||.|||.||.:..||....|.|||.||||.|:.:||||||||.|.|:.:.......|:.
Human   107 TSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASS 171

  Fly   140 YSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAAAV-ATNPMMATGMPPMGMPQMPTMQMPG 203
            .:..|||.|.:........:...|.||:..|...:...: |::...:.|.|....|::    .|.
Human   172 SASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRL----NPL 232

  Fly   204 HSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHP--HMMGSSA 248
            .|..|..|.|           |..||....:.|.:..|  :.:||||
Human   233 SSASASPPLP-----------PPLPAVCFSSAPLLDLPAGYELGSSA 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	32/55 (58%)
VAX2	NP_036608.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		9/32 (28%)
		Homeodomain	103..159	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..240		7/38 (18%)