Protein Alignment eve and ALX3

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 67/243 - (27%)
• Similarity: 97/243 - (39%)
• Gaps: 58/243 - (23%)

  Fly    42 PPSPNECLSSP---DNSLNGSRGS-----EIPADPSV-------------RRYRTAFTRDQLGRL 85
            |..|.:|...|   .::|.||.|.     .:|..|.:             ||.||.|:..||..|
Human   104 PQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEEL 168

  Fly    86 EKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMK-DKRQRIAVAW----PYAAVY----- 140
            ||.|.|.:|.....|.:||.:.:|.|:.::|||||||.| .||:|.....    |:.|.|
Human   169 EKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVL 233

  Fly   141 ----SDPAFAASILQAAANS----------VGMPYPPYAPAAAAAAAAAAAVATNPMMATGMPPM 191
                |.|....|:..:..:.          .|:|.|..:|.:....:.|..:.. |..:...|.:
Human   234 PRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGV-PAPSAAHPGI 297

  Fly   192 ----GMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAG 235
                |.|  ||:     .||:..||..|.|: :|..:..|..|..|.|
Human   298 YSIHGFP--PTL-----GGHSFEPSSDGDYK-SPSLVSLRVKPKEPPG 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	26/56 (46%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		67/243 (28%)
		PRK12323	<13..131	CDD:481241	8/26 (31%)
		Homeodomain	154..210	CDD:459649	26/55 (47%)