DRSC/TRiP Functional Genomics Resources

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Protein Alignment eve and EN1

DIOPT Version :10

Sequence 1:NP_523670.2 Gene:eve / 36039 FlyBaseID:FBgn0000606 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_001417.3 Gene:EN1 / 2019 HGNCID:3342 Length:392 Species:Homo sapiens


Alignment Length:118 Identity:41/118 - (34%)
Similarity:58/118 - (49%) Gaps:21/118 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 DASPV----DQKPLVVDLLATQYGKPQTPPPSPNECLSSPDNSLNGSRGSEIPA---DPSVRRYR 74
            :..||    .|:|||.              |:...|....|...:|.|..::..   :...:|.|
Human   257 NGGPVVKTDSQQPLVW--------------PAWVYCTRYSDRPSSGPRTRKLKKKKNEKEDKRPR 307

  Fly    75 TAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKR 127
            ||||.:||.||:.||....|::..||..||.:|:|.||.||:||||:|.|.|:
Human   308 TAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKK 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eveNP_523670.2 Homeodomain 71..127 CDD:459649 29/55 (53%)
EN1NP_001417.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..100
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 132..164
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 219..251
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 282..306 3/23 (13%)
Homeodomain 305..360 CDD:459649 29/54 (54%)
Engrail_1_C_sig 361..391 CDD:431338 41/118 (35%)
Blue background indicates that the domain is not in the aligned region.

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