Protein Alignment eve and Pitx3

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_006526827.1
• Gene: Pitx3 / 18742
• MGIID: 1100498
• Length: 388
• Species: Mus musculus
• Alignment Length: 337
• Identity: 88/337 - (26%)
• Similarity: 113/337 - (33%)
• Gaps: 108/337 - (32%)

  Fly    40 TP-PPSPNECLSSPDNSLNGSRGSEIPA----DPSV----RRYRTAFTRDQLGRLEKEFYKENYV 95
            || ||.|.......::|.:....:.:|.    |.|:    ||.||.||..||..||..|.:..|.
Mouse   109 TPHPPLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYP 173

  Fly    96 SRPRRCELAAQLNLPESTIKVWFQNRRMK-DKRQRIAVAW---------------PYAAVYSD-- 142
            ....|.|:|...||.|:.::|||:|||.| .||:|...|.               ||..||..
Mouse   174 DMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEVYPGYS 238

  Fly   143 ----------PAFAASILQAAANSVGM----PYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGM 193
                      |..||.....|.|||.:    ..|.::|.::.||:...:.|..|....|
Mouse   239 YGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG------ 297

  Fly   194 PQMPTMQMPGH-SGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHPHMMGSSATGSSYSAGA 257
                    ||. .|..|                   |||..|      |..:.|.|....|::.|
Mouse   298 --------PGALQGLGG-------------------APPGLA------PAAVSSGAVSCPYASAA 329

  Fly   258 AGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSAPS 322
            |....|..|           |.....|.        :||..||......||..        |.|:
Mouse   330 AAAAAAASS-----------PYVYRDPC--------NSSLASLRLKAKQHASF--------SYPA 367

  Fly   323 VPAPAPLTTTSP 334
            ||.|.|....||
Mouse   368 VPGPPPAANLSP 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	25/56 (45%)
Pitx3	XP_006526827.1	Homeodomain	149..205	CDD:459649	25/55 (45%)
		PTZ00395	<228..>322	CDD:185594	29/132 (22%)
		OAR	344..361	CDD:461067	5/24 (21%)