Protein Alignment eve and Nkx2-9

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_032727.2
• Gene: Nkx2-9 / 18094
• MGIID: 1270158
• Length: 235
• Species: Mus musculus
• Alignment Length: 237
• Identity: 72/237 - (30%)
• Similarity: 95/237 - (40%)
• Gaps: 51/237 - (21%)

  Fly    22 DQKPLVVDLLATQYGKPQTPPPSPNEC---LSSPDNSLNGSRGS---------EIP-ADPSVRR- 72
            |.||.|  ....|...|||.....:||   |||.::.|..|...         |.| :||..||
Mouse    21 DAKPRV--RREQQTCVPQTAAWLESECSHYLSSDESGLETSPADSSQLASLRRESPGSDPEKRRK 83

  Fly    73 YRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYA 137
            .|..|::.|...||:.|.::.|:|.|.|.:||..|.|..:.:|:||||.|.|.||.|.    |..
Mouse    84 RRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRA----PGI 144

  Fly   138 AVYSDPAFAASILQAA---ANSVGMPY-----PPYAPAAAAAAAAAAAVATNPMMATGMPPMGMP 194
            ...||.| |:|.|.||   ...|.:|.     ||.........:|......:..:||..|
Mouse   145 TEPSDMA-ASSDLHAAPGLLRRVVVPVLVHDRPPSNNGRGEGTSAVPQDKCSARLATACP----- 203

  Fly   195 QMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGP 236
                  :||::.. |..|..|.:          ||..|.|.|
Mouse   204 ------VPGYTAF-GPGSALGLF----------PAYQHLAPP 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	23/56 (41%)
Nkx2-9	NP_032727.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..86		9/34 (26%)
		Homeodomain	82..138	CDD:459649	22/55 (40%)