Protein Alignment eve and Nkx2-3

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_032725.1
• Gene: Nkx2-3 / 18089
• MGIID: 97348
• Length: 362
• Species: Mus musculus
• Alignment Length: 304
• Identity: 83/304 - (27%)
• Similarity: 109/304 - (35%)
• Gaps: 75/304 - (24%)

  Fly    12 HHAHHDA--SPVDQKPLVVDLLATQYGKPQTPPPSPNECLSSPDNSLNGSRGSEIPADPSVRRYR 74
            |....||  .|.:|:..||...:.:..:.:....:..:|.:|.|        .|.|...|.|:.|
Mouse    93 HTVLRDACSGPKEQEEEVVSERSQKSCQLKKSLEAAGDCKTSED--------GERPKPRSRRKPR 149

  Fly    75 TAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQR---------- 129
            ..|::.|:..||:.|.::.|:|.|.|..||:.|.|..:.:|:||||||.|.||||
Mouse   150 VLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTH 214

  Fly   130 ------IAVAWPYAAVYSDPAFAASILQAAANSVGMPY------------PPY------APAAAA 170
                  ..||.|.......|....|     |.:.|.||            |.|      |.||||
Mouse   215 APPPPPRRVAVPVLVRDGKPCVTPS-----AQTYGSPYGVGAGAYSYNSFPAYGYGNSAAAAAAA 274

  Fly   171 AAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAG 235
            |||||||.|.:.......|           ..|..|..|..|             |......||.
Mouse   275 AAAAAAAAAYSGSYGCAYP-----------TGGGGGGGGTAS-------------AATTAMQPAC 315

  Fly   236 PHMHHPHMMGSSATGSSYSAGAAGLL--GALPSATCYTGLGVGV 277
            ........:..|..|...|.|.|..|  ||...:.|..|...|:
Mouse   316 SATGGGSFVNVSNLGGFGSGGGAQPLHQGAAAGSACTQGTLQGI 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	23/55 (42%)
Nkx2-3	NP_032725.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..149		7/30 (23%)
		Homeodomain	146..202	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..222		2/18 (11%)