Protein Alignment eve and DLX5

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005212.1
• Gene: DLX5 / 1749
• HGNCID: 2918
• Length: 289
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 75/317 - (23%)
• Similarity: 111/317 - (35%)
• Gaps: 104/317 - (32%)

  Fly     2 HGY------------RTYNMESHHAHHDASPVDQKPLVVDLLAT---QYGKPQTPPPS----PNE 47
            |||            ..|..:.|..:..|.....|.......|:   |||......||    |.:
Human    56 HGYCSPTSASYGKALNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQPEK 120

  Fly    48 CLSSPD-NSLNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPE 111
            .::.|: ..:||.       ...||:.||.::..||..|::.|.|..|::.|.|.||||.|.|.:
Human   121 EVTEPEVRMVNGK-------PKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQ 178

  Fly   112 STIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAA 176
            :.:|:||||:|.|.|:                     |::...    || |.::|:
Human   179 TQVKIWFQNKRSKIKK---------------------IMKNGE----MP-PEHSPS--------- 208

  Fly   177 AVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHP 241
              :::||....      ||.|.:.           .|.|..|...:|            ||.|.|
Human   209 --SSDPMACNS------PQSPAVW-----------EPQGSSRSLSHH------------PHAHPP 242

  Fly   242 HMMGSSATGSSYSAGAAGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTL 298
              ..:.:..|||...         ||:.||.....:.....||..||...:..|.||
Human   243 --TSNQSPASSYLEN---------SASWYTSAASSINSHLPPPGSLQHPLALASGTL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	24/55 (44%)
DLX5	NP_005212.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49
		DLL_N	32..118	CDD:463567	13/61 (21%)
		Homeodomain	138..194	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..251		17/99 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..289		7/19 (37%)