Protein Alignment eve and Arx

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_031518.2
• Gene: Arx / 11878
• MGIID: 1097716
• Length: 564
• Species: Mus musculus
• Alignment Length: 263
• Identity: 89/263 - (33%)
• Similarity: 115/263 - (43%)
• Gaps: 45/263 - (17%)

  Fly    48 CLSSPDNSLNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPES 112
            |||:      ||...|.......|||||.||..||..||:.|.|.:|.....|.|||.:|:|.|:
Mouse   314 CLSA------GSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEA 372

  Fly   113 TIKVWFQNRRMK-DKRQRI-AVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPA-----AAA 170
            .::|||||||.| .||::. |...|....:..|..|...|....::  .|:||:.||     .||
Mouse   373 RVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDA--SPFPPHHPALDSAWTAA 435

  Fly   171 AAAAAAAVATNPMMATGMPPMGMPQMPTMQMP-GHSGHAG-----HP---SP-YGQYRYTPYHIP 225
            |||||||..:.|      ||.|...:|....| |.|...|     ||   || :|:...|  ..|
Mouse   436 AAAAAAAFPSLP------PPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFST--MAP 492

  Fly   226 ARPAPPHPAGPHMHHPHMMGSSATGS-----------SYSAGAAGLLGALPSATCYTGLGVGVPK 279
            ...|....|......|.:.|:.|:|:           ..|:.||..|.|...|...|.|.: :|.
Mouse   493 LTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNI-LPG 556

  Fly   280 TQT 282
            |.|
Mouse   557 TST 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	29/56 (52%)
Arx	NP_031518.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..79
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..264
		Homeodomain	331..387	CDD:459649	29/55 (53%)
		OAR	528..546	CDD:461067	5/17 (29%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	532..545		5/12 (42%)