Protein Alignment CG12134 and Wdr89

DIOPT Version :10

• Sequence 1: NP_610542.1
• Gene: CG12134 / 36038
• FlyBaseID: FBgn0033471
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_006240295.1
• Gene: Wdr89 / 314243
• RGDID: 1307393
• Length: 397
• Species: Rattus norvegicus
• Alignment Length: 383
• Identity: 113/383 - (29%)
• Similarity: 171/383 - (44%)
• Gaps: 58/383 - (15%)

  Fly    58 YVLSLAADQGFSRMAAGL-----SNSAVHIYNLDSGAGKLENFSYLPPTDSPQSVSICGVRFLDE 117
            |:|.:...:.......||     ||.::.||:.:: ...|..||     .||..::  ||||.:
  Rat    36 YLLGIDTSKTVPAEKGGLVAVLCSNGSIRIYDKET-LNLLREFS-----GSPGLLN--GVRFAN- 91

  Fly   118 GPHNILVGTTDGYVRLYDLRLRGEQARFKYTQHPNVPPVPKSLSCFDRNANGRIICCGTEQFHSN 182
            ...|:...:|||.|:.:|.||..|:....:..:|:     .....||.|....|||.|.|:...:
  Rat    92 SCDNVYSASTDGTVKCWDARLASEKPAQLFKGYPS-----NIFISFDVNCKDHIICAGAEKVEDD 151

  Fly   183 AFLVFFDVR-------ERQQMGVYFESHEDDITSLRFHAQNPDLLATGSVDGLVNVFDVKEPDED 240
            |.|||:|.|       .|..:|.|.|:|.||||.:|||..||:::.:||.||||||||:...:|:
  Rat   152 ALLVFWDARFTSQDLSTRDPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDLSVDNEE 216

  Fly   241 EALLNTFNTESSVARLAWHRNVYDKDIISCVTTTGDFKSYECE--EGDE-VASFERPDVTAAIRR 302
            :||:.|.|:.|||:.:.|....|.:  |.|:|....|..::..  :.|| :......||......
  Rat   217 DALVATCNSVSSVSCIGWCGRDYKQ--IYCMTHDEGFCWWDLNHLDTDEPITCLNIQDVRDVTDV 279

  Fly   303 KKAANFNLINA--HNQEDGGVFLLAGTNFNKGEILRSVSVTSKNSLQPLANFQ-GNKQIVRDSLF 364
            |:.....||..  |...| .:|::.|||..|..:|.    .:|..|..:.:.| |:...||...:
  Rat   280 KEGHLDYLIGGLYHENMD-RLFVIGGTNLGKIHLLS----CTKTGLSHVTSLQGGHAATVRSFCW 339

  Fly   365 DSKRSLLFTGGESGIVTVWAQDASGTAF-------------------SSEKLKARKEK 403
            ......|.||||...:.:|...|....|                   ||:..|.||::
  Rat   340 TVSEDSLLTGGEDAQLLLWKPGAVEKTFTKKDSLKIASSVQQRVRVHSSDSYKKRKQQ 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12134	NP_610542.1	WD40	56..384	CDD:475233	105/343 (31%)
		WD40 repeat	59..101	CDD:293791	10/46 (22%)
		WD40 repeat	108..146	CDD:293791	13/37 (35%)
		WD40 repeat	153..201	CDD:293791	17/54 (31%)
		WD40 repeat	207..248	CDD:293791	21/40 (53%)
		WD40 repeat	300..353	CDD:293791	13/54 (24%)
		WD40 repeat	359..390	CDD:293791	9/30 (30%)
Wdr89	XP_006240295.1	WD40	51..359	CDD:475233	103/328 (31%)
		WD40 repeat	85..123	CDD:293791	13/40 (33%)
		WD40 repeat	128..176	CDD:293791	16/47 (34%)
		WD40 repeat	184..224	CDD:293791	20/39 (51%)
		WD40 repeat	229..269	CDD:293791	9/41 (22%)
		WD40 repeat	288..327	CDD:293791	11/43 (26%)
		WD40 repeat	334..358	CDD:293791	7/23 (30%)