Protein Alignment CG12134 and wdr-23

DIOPT Version :9

• Sequence 1: NP_001369072.1
• Gene: CG12134 / 36038
• FlyBaseID: FBgn0033471
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_492124.1
• Gene: wdr-23 / 172518
• WormBaseID: WBGene00008419
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 498
• Identity: 94/498 - (18%)
• Similarity: 175/498 - (35%)
• Gaps: 156/498 - (31%)

  Fly    25 IGDEDTCSAQDLAAEFQLKYKPQDEVSVSLQREYVLSLAADQGFSRMAAGLSN--SAVHIYNLDS 87
            |||.::|:  .|..|...:..|:.  |.|...|::|    ::...:....:||  :...:.|
 Worm    97 IGDPESCT--QLRNEINSRCGPRP--STSNNMEFIL----NRDLQKRGTSISNPRTVARVLN--- 150

  Fly    88 GAGKLENFSYLP----PTDSPQSVSICGVRFLDEGPHNILVGTTDGYVRLY-------------- 134
                    |:||    ..|...:.|.| .:::..|. .|:|.:.|..:|.|
 Worm   151 --------SHLPNQKRRVDRVATKSFC-TQYIQNGT-KIVVASQDEKIRFYQRNPDKSKYRSKYM 205

  Fly   135 ---DLR--------------LRGE------------QARFKYTQHPNVPPVPKSLS--------- 161
               :||              |.|:            ..:..:|:..|:...|..|:
 Worm   206 KSDELRVDQCGWSILDTAISLNGDLIAYGTWKDAVFVGKLDFTERQNITWFPIDLNGEPGRDHCA 270

  Fly   162 --CFDRNANGRIICCGTEQFHSNAFLVFFDVRERQQMGVYFESHEDDITSLRFHAQNPDLLATGS 224
              |...:.:...|.|||.|:..:.    |||.:|:::.....:||||:.|:.|.....:|:.:..
 Worm   271 VFCVKFSDSSEQIVCGTSQYSIHV----FDVEQRRRIRTIVNAHEDDVNSVCFADLGSNLIYSAG 331

  Fly   225 VDGLVNVFDVK-------EP------------------DEDEALLNTFNTESSVARLAWHRNVYD 264
            .||||.|:|.:       ||                  ||...|.|:.:....|..|....|:..
 Worm   332 DDGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQTIKVWDLRKFSNMSG 396

  Fly   265 KDII-SCVTTT-GDFKSYECEEG--DEVASFERPDVTAAIRRKKAANFNLINAH--NQEDGGVFL 323
            .:.. :||.:. .|::......|  ..||.    |.:....|..:....|:.|:  .:..|..::
 Worm   397 VEATRACVQSQHWDYRWQPAPPGLCQPVAG----DTSVMTLRGHSVLHTLVRANFSPESTGRRYI 457

  Fly   324 LAGTNFNKGEI----LRSVSVTSKNSLQPLANFQGNKQIVRDSLFDSKRSLLFTGGESGIVTVWA 384
            ..|.  .:||:    :.|.:|:.:        .:|:..:||:..:....:.:.:....|:.|||.
 Worm   458 YTGC--ARGEVVVYDIMSGTVSRR--------LKGHTAVVRECDWHPTENEIVSSAWDGVTTVWT 512

  Fly   385 ----------------------QDASGTAFSSEKLKARKEKKS 405
                                  :|:....|...|.:.|:::|:
 Worm   513 WDERQEGVIAPYDHPNISQFGDEDSCDELFQPVKKQCRRQRKT 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12134	NP_001369072.1	WD40	56..384	CDD:421866	79/422 (19%)
		WD40 repeat	59..101	CDD:293791	7/47 (15%)
		WD40 repeat	108..146	CDD:293791	12/80 (15%)
		WD40 repeat	153..201	CDD:293791	12/58 (21%)
		WD40 repeat	207..248	CDD:293791	15/65 (23%)
		WD40 repeat	300..353	CDD:293791	9/58 (16%)
		WD40 repeat	359..390	CDD:293791	7/52 (13%)
wdr-23	NP_492124.1	WD40	119..511	CDD:225201	80/426 (19%)
		WD40 repeat	167..205	CDD:293791	8/39 (21%)
		WD40	168..514	CDD:295369	70/365 (19%)
		WD40 repeat	220..269	CDD:293791	6/48 (13%)
		WD40 repeat	271..307	CDD:293791	10/39 (26%)
		WD40 repeat	315..356	CDD:293791	11/40 (28%)
		WD40 repeat	362..434	CDD:293791	14/75 (19%)
		WD40 repeat	442..481	CDD:293791	8/48 (17%)
		WD40 repeat	487..511	CDD:293791	4/23 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000