Protein Alignment CG12134 and wdr89

DIOPT Version :10

• Sequence 1: NP_610542.1
• Gene: CG12134 / 36038
• FlyBaseID: FBgn0033471
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001161430.1
• Gene: wdr89 / 100148281
• ZFINID: ZDB-GENE-090319-3
• Length: 379
• Species: Danio rerio
• Alignment Length: 410
• Identity: 123/410 - (30%)
• Similarity: 184/410 - (44%)
• Gaps: 79/410 - (19%)

  Fly    28 EDTCSAQDLAAEFQLKYKPQDEVSVSLQREYVL--SLAADQGFSRMAAGLSNSAVHIYNLDS--G 88
            |||.....:|...|    |.:..       |:|  ||||.   ..:|...||.:||::|.::  .
Zfish     5 EDTFRTLAIARRLQ----PSEAT-------YILDVSLAAS---DVLAVCCSNHSVHLHNRETLHQ 55

  Fly    89 AGKLENFSYLPPTDSPQSVSICGVRFLDEGPHNILVGTTDGYVRLYDLRLRGEQARFKYTQHPNV 153
            .|:.:.          .:..:|||||....||.:..|:.||.:|.:|:|.....:...:...|.
Zfish    56 VGQFQG----------HTAPVCGVRFSHMSPHLLFSGSADGTIRSWDIRRPDSDSVQVFRSDPT- 109

  Fly   154 PPVPKSLSCFDRNANGRIICCGTEQFHSNAFLVFFD---VRERQQMGVYFESHEDDITSLRFHAQ 215
                .|...||.:...|::|.||||...::||||:|   |::|..:|||.|||.||:|:::||.|
Zfish   110 ----HSYCSFDVSCTDRVLCAGTEQVEEDSFLVFWDARMVQDRGPLGVYSESHSDDVTAVKFHPQ 170

  Fly   216 NPDLLATGSVDGLVNVFDVKEPDEDEALLNTFNTESSVARLAWHRNVYDKDIISCVTTTGDFKSY 280
            ..|.||:|..||||||||:....||:||:.|.|..||.:.|.|...  |.|.:.|:|.
Zfish   171 QADRLASGGTDGLVNVFDLSLGGEDDALVTTCNCNSSASSLCWTGK--DLDRLLCLTH------- 226

  Fly   281 ECEEGDEVASFERPDVTAAIRRKKAANFN-LINAHNQEDGGV---FLLAGT------------NF 329
              :||..:....|||....:....:|:.. |:    |...||   :.:.||            ..
Zfish   227 --DEGLHLWDVARPDSDDTLTLLSSADARPLV----QLPDGVSLEYFIGGTWLPDEERTLLVGGS 285

  Fly   330 NKGEI-LRSVSVTSKNSLQPLANFQGNKQIVRDSLFDSKRSLLFTGGESGIVTVWAQDA------ 387
            |:||: |...|.:....::.|..  |:...||...:|:....|.||||.|.:..|...|
Zfish   286 NQGELHLLDCSGSGLRLIKSLKG--GHSATVRCFQWDAIGRSLVTGGEDGQLLQWKAGAEEISVG 348

  Fly   388 ---SGTAFSSEKLKARKEKK 404
               |..:.||.:||.:..:|
Zfish   349 KKESLKSISSMQLKTKAHRK 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12134	NP_610542.1	WD40	56..384	CDD:475233	109/351 (31%)
		WD40 repeat	59..101	CDD:293791	12/45 (27%)
		WD40 repeat	108..146	CDD:293791	13/37 (35%)
		WD40 repeat	153..201	CDD:293791	19/50 (38%)
		WD40 repeat	207..248	CDD:293791	21/40 (53%)
		WD40 repeat	300..353	CDD:293791	13/69 (19%)
		WD40 repeat	359..390	CDD:293791	12/39 (31%)
wdr89	NP_001161430.1	WD40 repeat	25..60	CDD:293791	12/37 (32%)
		WD40	33..339	CDD:475233	103/340 (30%)
		WD40 repeat	67..107	CDD:293791	13/39 (33%)
		WD40 repeat	114..155	CDD:293791	17/40 (43%)
		WD40 repeat	162..203	CDD:293791	21/40 (53%)
		WD40 repeat	208..233	CDD:293791	8/35 (23%)
		WD40 repeat	255..307	CDD:293791	11/55 (20%)
		WD40 repeat	314..338	CDD:293791	9/23 (39%)