Protein Alignment eIF3j and EIF3J

DIOPT Version :10

• Sequence 1: NP_610541.1
• Gene: eIF3j / 36037
• FlyBaseID: FBgn0027619
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_003749.2
• Gene: EIF3J / 8669
• HGNCID: 3270
• Length: 258
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 100/249 - (40%)
• Similarity: 149/249 - (59%)
• Gaps: 15/249 - (6%)

  Fly     2 ADDWESAADS-EVVIRPT---AAASVNKWEGEDEDEDIKDSWEDEEEKKDEEKPTKTEA--PAKP 60
            :|.|::.|.| |..:|..   ..|..::|||||||||:||:|:|::::|.||...|.|.  ..|.
Human    11 SDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKK 75

  Fly    61 KPNKALKAKLEQQALLEEEAEAKRLAN------LSPAEKLAEKLRLQKIQEASDLKHAQEAFGVT 119
            |..:.:|.|..||...:||.: |||..      |:|.|:||:||||:|:||.|||:.|:|.|||.
Human    76 KIAEKIKEKERQQKKRQEEIK-KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVN 139

  Fly   120 STCGGLDAFNPETKEEFKEFGATLSWKVGQFRESEHFPQFVEDLVRSLCVNLSAADIKKVKMNVE 184
            :...|:||.||.::::|.|||..|..|:.|:.:|.::..|:|.|||.:|::|...|:||:..::.
Human   140 NAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLT 204

  Fly   185 ILHSEKLKLEKANAKKPAGKG--KGKVTLRTENDDIDGYQKYGNDFTEDYDDFM 236
            :|.|||.|.||.:..|...||  .|.....|..||:..|..|...:.:||:|||
Human   205 VLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDGGYVQDYEDFM 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3j	NP_610541.1	eIF3_subunit	3..236	CDD:462530	98/246 (40%)
EIF3J	NP_003749.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108		36/97 (37%)
		Sufficient for interaction with EIF3B	2..69		24/57 (42%)
		eIF3_subunit	12..258	CDD:462530	98/246 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..238		5/20 (25%)
		Promotes stable association with the 40S ribosome	243..258		5/14 (36%)