DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF3j and EIF3J

DIOPT Version :9

Sequence 1:NP_001286260.1 Gene:eIF3j / 36037 FlyBaseID:FBgn0027619 Length:236 Species:Drosophila melanogaster
Sequence 2:NP_003749.2 Gene:EIF3J / 8669 HGNCID:3270 Length:258 Species:Homo sapiens


Alignment Length:249 Identity:100/249 - (40%)
Similarity:149/249 - (59%) Gaps:15/249 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 ADDWESAADS-EVVIRPT---AAASVNKWEGEDEDEDIKDSWEDEEEKKDEEKPTKTEA--PAKP 60
            :|.|::.|.| |..:|..   ..|..::|||||||||:||:|:|::::|.||...|.|.  ..|.
Human    11 SDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKK 75

  Fly    61 KPNKALKAKLEQQALLEEEAEAKRLAN------LSPAEKLAEKLRLQKIQEASDLKHAQEAFGVT 119
            |..:.:|.|..||...:||.: |||..      |:|.|:||:||||:|:||.|||:.|:|.|||.
Human    76 KIAEKIKEKERQQKKRQEEIK-KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVN 139

  Fly   120 STCGGLDAFNPETKEEFKEFGATLSWKVGQFRESEHFPQFVEDLVRSLCVNLSAADIKKVKMNVE 184
            :...|:||.||.::::|.|||..|..|:.|:.:|.::..|:|.|||.:|::|...|:||:..::.
Human   140 NAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLT 204

  Fly   185 ILHSEKLKLEKANAKKPAGKG--KGKVTLRTENDDIDGYQKYGNDFTEDYDDFM 236
            :|.|||.|.||.:..|...||  .|.....|..||:..|..|...:.:||:|||
Human   205 VLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDGGYVQDYEDFM 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF3jNP_001286260.1 eIF3_subunit 3..236 CDD:285763 98/246 (40%)
EIF3JNP_003749.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..108 36/97 (37%)
Sufficient for interaction with EIF3B 2..69 24/57 (42%)
eIF3_subunit 12..258 CDD:400769 98/246 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 217..238 5/20 (25%)
Promotes stable association with the 40S ribosome 243..258 5/14 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165158725
Domainoid 1 1.000 172 1.000 Domainoid score I3736
eggNOG 1 0.900 - - E1_KOG4813
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H37845
Inparanoid 1 1.050 173 1.000 Inparanoid score I4087
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG55542
OrthoDB 1 1.010 - - D1565510at2759
OrthoFinder 1 1.000 - - FOG0004066
OrthoInspector 1 1.000 - - oto90287
orthoMCL 1 0.900 - - OOG6_103515
Panther 1 1.100 - - LDO PTHR21681
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X5085
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1514.770

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