Protein Alignment CG12133 and Prss8

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_579929.1
• Gene: Prss8 / 76560
• MGIID: 1923810
• Length: 339
• Species: Mus musculus
• Alignment Length: 284
• Identity: 87/284 - (30%)
• Similarity: 133/284 - (46%)
• Gaps: 61/284 - (21%)

  Fly    62 IVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCL---NVNDFYVARVRL 123
            |.||..|:..|:||.|.:.|:.       :.:|.|||:::::|::||||.   :..:.|  .|:|
Mouse    45 ITGGGSAKPGQWPWQVSITYDG-------NHVCGGSLVSNKWVVSAAHCFPREHSREAY--EVKL 100

  Fly   124 GEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQI 188
            |.|..::..:.|.:...|:|             :.|..|  |......||||:||.|.|.::..|
Mouse   101 GAHQLDSYSNDTVVHTVAQI-------------ITHSSY--REEGSQGDIALIRLSSPVTFSRYI 150

  Fly   189 RPICIWPGIELSTSSFKN-FPFQIAGWG---DSGLQQKSTVLRQGTISGMSPDEC-----LNRYP 244
            ||||    :..:.:||.| ....:.|||   .|...|....|:|..:..:|.:.|     :|..|
Mouse   151 RPIC----LPAANASFPNGLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYNINAVP 211

  Fly   245 ----TLLVDKDIQICAMGW--DGTDTGLGDSGSPLMASVGRGADQFYYLAGITSYG---GGPSSY 300
                |:..|   .:|| |:  .|.|...||||.||...:    :..:|||||.|:|   |.|:.
Mouse   212 EEPHTIQQD---MLCA-GYVKGGKDACQGDSGGPLSCPM----EGIWYLAGIVSWGDACGAPNR- 267

  Fly   301 GYGPAVYTKTSSYYEWIKKKINDI 324
               |.|||.||:|..||...:.::
Mouse   268 ---PGVYTLTSTYASWIHHHVAEL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	85/275 (31%)
Prss8	NP_579929.1	Tryp_SPc	45..284	CDD:238113	87/278 (31%)