Protein Alignment CG12133 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 90/312 - (28%)
• Similarity: 135/312 - (43%)
• Gaps: 70/312 - (22%)

  Fly    31 LVHMVFTCCPMVAGDKLPDSRVC-----GQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRP 90
            :::::....|::|      ||..     ||:.....||||.||..:::||.|.|....      |
Human     1 MLNLLLLALPVLA------SRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHG------P 53

  Fly    91 SPM--CAGSLIASRYVLTAAHCL--NVNDFYVARVRLGE-HDTENDPDYTWLPNGAKIWAPAHVD 150
            ..|  |.||||..::|||||||:  :|.|....||:|.| |....|   ..||
Human    54 YWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLP------------ 103

  Fly   151 IDVDLRVPHEQYYTRN-GRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSF-KNFPFQIAG 213
              |...:.|.|:||.. |.   |||||.|:..|..:..:..:.:.|..|    :| ...|..:.|
Human   104 --VSRIIVHPQFYTAQIGA---DIALLELEEPVNVSSHVHTVTLPPASE----TFPPGMPCWVTG 159

  Fly   214 WGDSGLQQK---STVLRQGTISGMSPDECLNRY-------PTLLVDKDIQICAMGWDGTDTGLGD 268
            |||....::   ...|:|..:..|....|..:|       ..:.:.:|..:|| |....|:..||
Human   160 WGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCA-GNTRRDSCQGD 223

  Fly   269 SGSPLMASVGRGADQFYYLAGITSYGGG---PSSYGYGPAVYTKTSSYYEWI 317
            ||.||:..|    :..:..||:.|:|.|   |:.    |.:||:.:.|.:||
Human   224 SGGPLVCKV----NGTWLQAGVVSWGEGCAQPNR----PGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	82/274 (30%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	84/276 (30%)