Protein Alignment CG12133 and TPSB2

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 89/311 - (28%)
• Similarity: 135/311 - (43%)
• Gaps: 68/311 - (21%)

  Fly    31 LVHMVFTCCPMVAGDKLPDSRVC-----GQSPPSSYIVGGMEAQSNQFPWTVLLGY-EAYTAKQR 89
            :::::....|::|      ||..     ||:.....||||.||..:::||.|.|.. :.|...
Human     1 MLNLLLLALPVLA------SRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMH-- 57

  Fly    90 PSPMCAGSLIASRYVLTAAHCL--NVNDFYVARVRLGE-HDTENDPDYTWLPNGAKIWAPAHVDI 151
               .|.||||..::|||||||:  :|.|....||:|.| |....|   ..||
Human    58 ---FCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLP------------- 103

  Fly   152 DVDLRVPHEQYYTRN-GRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSF-KNFPFQIAGW 214
             |...:.|.|:||.. |.   |||||.|:..|..:..:..:.:.|..|    :| ...|..:.||
Human   104 -VSRIIVHPQFYTAQIGA---DIALLELEEPVNVSSHVHTVTLPPASE----TFPPGMPCWVTGW 160

  Fly   215 GDSGLQQK---STVLRQGTISGMSPDECLNRY-------PTLLVDKDIQICAMGWDGTDTGLGDS 269
            ||....::   ...|:|..:..|....|..:|       ..:.:.:|..:|| |....|:..|||
Human   161 GDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCA-GNTRRDSCQGDS 224

  Fly   270 GSPLMASVGRGADQFYYLAGITSYGGG---PSSYGYGPAVYTKTSSYYEWI 317
            |.||:..|    :..:..||:.|:|.|   |:.    |.:||:.:.|.:||
Human   225 GGPLVCKV----NGTWLQAGVVSWGEGCAQPNR----PGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	81/273 (30%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	83/275 (30%)