Protein Alignment CG12133 and c1s

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_002941253.2
• Gene: c1s / 613055
• XenbaseID: XB-GENE-995410
• Length: 691
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 94/312 - (30%)
• Similarity: 137/312 - (43%)
• Gaps: 87/312 - (27%)

  Fly    52 VCG--QSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVN 114
            |||  ||..|..|.||..|:..||||.:     .:|..:    :..||||:.|:||||||.:|..
 Frog   425 VCGVHQSDKSGRIFGGTRAKPGQFPWMI-----QFTDIE----LGGGSLISDRWVLTAAHVVNKK 480

  Fly   115 DFYVARVRLGEHDTENDPDYTWLPN-----------GAKIWAPAHVDIDVDLRVPHEQYY----T 164
            .|          .|.......:.||           ..||             :.|..|.    |
 Frog   481 IF----------PTMFGGVMKFFPNTNLQSQEKRLQAKKI-------------IIHPLYQDNEDT 522

  Fly   165 RNGRHY-NDIALLRLKSRVKYTLQIRPICIWP--GI-----ELSTSSFKNFPFQIAGWGDSGLQQ 221
            ....:: |||||::|..:||....|.|||: |  |:     |::|         |||||.:..::
 Frog   523 EGQSNFDNDIALVQLTKKVKLGSCISPICL-PRRGLAPVVNEVAT---------IAGWGKTEKRE 577

  Fly   222 KSTVLRQGTISGMSPDECLNR-------YPTLLVDKDIQICAMGWDGTDTGLGDSGSPLMASVGR 279
            .:..|:..:||..|.|:|...       .|.:|       ||....|.|:..||||.|||.:..:
 Frog   578 SAVNLQFASISLSSMDKCKKATGGKGYFTPNML-------CAGSDVGKDSCNGDSGGPLMFTDPQ 635

  Fly   280 GADQFYYLAGITSYGGGPSSYG-YGPAVYTKTSSYYEWIKKKINDIAEDERK 330
            .:.:. |:|||.|:  ||...| ||  :|||..:|.:||::.|..:..:|::
 Frog   636 DSSKM-YMAGIVSW--GPRDCGTYG--LYTKVDNYLDWIEETIAAVEREEQE 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	84/285 (29%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:464251
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	6/10 (60%)
		Tryp_SPc	436..669	CDD:214473	84/286 (29%)