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Protein Alignment CG12133 and TMPRSS4

DIOPT Version :10

Sequence 1:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_005271670.1	Gene:	TMPRSS4 / 56649	HGNCID:	11878	Length:	494	Species:	Homo sapiens

Alignment Length:	278	Identity:	89/278 - (32%)
Similarity:	137/278 - (49%)	Gaps:	57/278 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 CGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVN-DF 116
            ||:|..:..:||..||..:.:||.|.:.|:    ||.   :|.||::...:|||||||...: |.
Human   196 CGKSLKTPRVVGVEEASVDSWPWQVSIQYD----KQH---VCGGSILDPHWVLTAAHCFRKHTDV 253

  Fly   117 YVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSR 181
            :..:||.|.....:.|...    .|||     :.|:.:...|.:          |||||::|:..
Human   254 FNWKVRAGSDKLGSFPSLA----VAKI-----IIIEFNPMYPKD----------NDIALMKLQFP 299

  Fly   182 VKYTLQIRPICIWPGI--ELSTSSFKNFPFQIAGWG----DSGLQQKSTVLRQGTISGMSPDECL 240
            :.::..:||||: |..  ||:.::    |..|.|||    :.|  :.|.:|.|.::..:....|.
Human   300 LTFSGTVRPICL-PFFDEELTPAT----PLWIIGWGFTKQNGG--KMSDILLQASVQVIDSTRCN 357

  Fly   241 --NRYPTLLVDKDIQICA-MGWDGTDTGLGDSGSPLMASVGRGADQFYYLAGITSYG---GGPSS 299
              :.|...:.:|  .:|| :...|.||..||||.|||..    :|| :::.||.|:|   ||||:
Human   358 ADDAYQGEVTEK--MMCAGIPEGGVDTCQGDSGGPLMYQ----SDQ-WHVVGIVSWGYGCGGPST 415

  Fly   300 YGYGPAVYTKTSSYYEWI 317
                |.||||.|:|..||
Human   416 ----PGVYTKVSAYLNWI 429

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.