Protein Alignment CG12133 and KLK7

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 75/286 - (26%)
• Similarity: 113/286 - (39%)
• Gaps: 64/286 - (22%)

  Fly    54 GQSPPSSYIVGGMEAQSNQFPWTVLL--GYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDF 116
            |:......|:.|........||.|.|  |.:.:         |.|.|:..|:||||||| .:|::
Human    22 GEEAQGDKIIDGAPCARGSHPWQVALLSGNQLH---------CGGVLVNERWVLTAAHC-KMNEY 76

  Fly   117 YVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSR 181
               .|.||. ||..|.            ....:......|  |..|.|:.  |.||:.|::|.|:
Human    77 ---TVHLGS-DTLGDR------------RAQRIKASKSFR--HPGYSTQT--HVNDLMLVKLNSQ 121

  Fly   182 VKYTLQIRPI-----CIWPGIELSTSSFKNFPFQIAGWGDSGLQQKS--TVLRQGTISGMSPDEC 239
            .:.:..::.:     |..||...:          ::|||.:.....:  :.|....:..:||.:|
Human   122 ARLSSMVKKVRLPSRCEPPGTTCT----------VSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176

  Fly   240 LNRYPTLLVDKDIQICAMGWDGTDTGL-GDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYG 303
            ...|..||  ::..:||...|...... ||||.||   |.||.     |.|:.|:|..|......
Human   177 TKVYKDLL--ENSMLCAGIPDSKKNACNGDSGGPL---VCRGT-----LQGLVSWGTFPCGQPND 231

  Fly   304 PAVYTKTSSYYEWIKKKINDIAEDER 329
            |.|||:...:.:|    |||..:..|
Human   232 PGVYTQVCKFTKW----INDTMKKHR 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	69/264 (26%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	70/269 (26%)