Protein Alignment CG12133 and KLK15

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 88/295 - (29%)
• Similarity: 116/295 - (39%)
• Gaps: 81/295 - (27%)

  Fly    44 GDKLPDSRVCGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAA 108
            ||||.:...|  :|.|.             ||.|.| ||      |....|..|||:..:||:||
Human    19 GDKLLEGDEC--APHSQ-------------PWQVAL-YE------RGRFNCGASLISPHWVLSAA 61

  Fly   109 HCLNVNDFYVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDI 173
            ||.:    ...|||||||:.........|...:::             :||.:|..|:  |.|||
Human    62 HCQS----RFMRVRLGEHNLRKRDGPEQLRTTSRV-------------IPHPRYEARS--HRNDI 107

  Fly   174 ALLRLKSRVKYTLQIRPI-----CIWPGIELSTSSFKNFPFQIAGWGDSGLQQKST--------- 224
            .||||....:...|:||.     |..|| |...         ::|||.....:..|
Human   108 MLLRLVQPARLNPQVRPAVLPTRCPHPG-EACV---------VSGWGLVSHNEPGTAGSPRSQVS 162

  Fly   225 ---VLRQGTISGMSPDECLNRYPTLLVDKDIQICAMGWD--GTDTGLGDSGSPLMASVGRGADQF 284
               .|....||.:|...|...||..|.  :..:|| |.:  |.::..||||.||:..
Human   163 LPDTLHCANISIISDTSCDKSYPGRLT--NTMVCA-GAEGRGAESCEGDSGGPLVCG-------- 216

  Fly   285 YYLAGITSYGGGPSSYGYGPAVYTKTSSYYEWIKK 319
            ..|.||.|:|..|......|.||||...|.|||::
Human   217 GILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRE 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	79/273 (29%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	82/285 (29%)