Protein Alignment CG12133 and Tmprss2

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 273
• Identity: 74/273 - (27%)
• Similarity: 124/273 - (45%)
• Gaps: 49/273 - (17%)

  Fly    60 SYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFYVARVRLG 124
            |.||||:.|....:||.|.|..:..       .:|.||:|...:::|||||:
Mouse   252 SRIVGGLNASPGDWPWQVSLHVQGV-------HVCGGSIITPEWIVTAAHCV------------- 296

  Fly   125 EHDTENDPDYTW------LPNGAKIWAPAHVDIDVDLRVPHEQY--YTRNGRHYNDIALLRLKSR 181
             .:..:.|.| |      |......:...|   .|:..:.|..|  .|:|    |||||::|::.
Mouse   297 -EEPLSSPRY-WTAFAGILRQSLMFYGSRH---QVEKVISHPNYDSKTKN----NDIALMKLQTP 352

  Fly   182 VKYTLQIRPICI-WPGIELSTSSFKNFPFQIAGWGDSGLQQK-STVLRQGTISGMSPDECLNRYP 244
            :.:...::|:|: .||:.|....    ...|:|||.:..:.| |.||....:..:.|.:|.::|.
Mouse   353 LAFNDLVKPVCLPNPGMMLDLDQ----ECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYI 413

  Fly   245 TLLVDKDIQICAMGWDGT-DTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYT 308
            ...:.....|||....|: |:..||||.||: ::..|   .::|.|.||:|.| .:....|.||.
Mouse   414 YNNLITPAMICAGFLQGSVDSCQGDSGGPLV-TLKNG---IWWLIGDTSWGSG-CAKALRPGVYG 473

  Fly   309 KTSSYYEWIKKKI 321
            ..:.:.:||.:::
Mouse   474 NVTVFTDWIYQQM 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	71/265 (27%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:464747
		Tryp_SPc	254..485	CDD:238113	73/268 (27%)