DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12133 and masp2

DIOPT Version :9

Sequence 1:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	328	Identity:	93/328 - (28%)
Similarity:	150/328 - (45%)	Gaps:	68/328 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KSQYRNKLCNINPFAHELVHMVFTCCPMVAGDKLPDSRVCGQSPPSS--YIVGGMEAQSNQFPWT 76
            |.:||   |..:.|..::.....|  |.:.   :||   ||:..|::  .||||..|...:|||.
Frog   405 KGEYR---CGADGFWEDIESEKKT--PPIC---VPD---CGKRKPAAAGRIVGGEFANVGEFPWQ 458

  Fly    77 VLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCL-NVNDFYVARVRLGEHDTENDPDYTWLPNG 140
            |.:...        :....|:|:...::|||||.: :.:|.....:::|...|::.       |.
Frog   459 VFINAN--------NERGGGALLLDNWILTAAHVVYSYDDLSSILIKMGFLSTQDS-------NY 508

  Fly   141 AKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQ-IRPICIWPGIE----LS 200
            .:.| |..|.|       ||.|  :.|.:.|||||::||::|..:.: |..||: |..|    :|
Frog   509 IRGW-PEAVFI-------HEGY--KPGHYNNDIALIKLKNKVPLSEESILGICL-PTKEKSYHIS 562

  Fly   201 TSSFKNFPFQIAGWGDSGLQQKSTVLRQGTISGMSPDECLNRYPTL----LVDKDIQICAMGWDG 261
            .....|....:||||.:..|:.|..||...::.:....|...|..|    :|.::: |||    |
Frog   563 HKDDDNHVGLVAGWGLTEAQRSSRKLRFVEVNIVDHSTCKAEYAKLDAQYIVTENM-ICA----G 622

  Fly   262 TDTGL-----GDSGSPLMASVGRGADQFYYLAGITSYG---GGPSSYGYGPAVYTKTSSYYEWIK 318
            .:.|:     ||||..|  :......:.:::.||.|:|   |....||    ||||.::|.:||:
Frog   623 FEIGVKDSCAGDSGGAL--AFMNAESKKWFVGGIVSWGVGCGVARQYG----VYTKVTNYLDWIE 681

  Fly   319 KKI 321
            |.|
Frog   682 KTI 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..320	CDD:238113	79/275 (29%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	77/272 (28%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056
		CCP	365..430	CDD:153056	7/32 (22%)
		Tryp_SPc	443..680	CDD:214473	77/273 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910