DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12133 and modSP

DIOPT Version :9

Sequence 1:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	363	Identity:	83/363 - (22%)
Similarity:	120/363 - (33%)	Gaps:	86/363 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 YRNK-LCNIN--------PFAHELVHMVFTCCPMVAGDK----LPDSRV---------------- 52
            |..| ||..|        ||......:.|.|.   .|.|    ||:.|.
  Fly   296 YSTKALCTHNGQQVECRKPFHPPGTEVKFVCS---TGFKTLSPLPEMRCMKGGYWNRGRQRCEQD 357

  Fly    53 CGQ--SPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVND 115
            |||  :|...:..||....:...||.|  |...:..::.....|.|||:....|:|||||:
  Fly   358 CGQLATPIKQFSSGGYTINNTVVPWHV--GLYVWHNEKDYHFQCGGSLLTPDLVITAAHCV---- 416

  Fly   116 FYVARVRLG-EHDTENDPDYTWLPNGAKIW------APAHVDIDVDLRVPHEQYYTRNGRHYNDI 173
             |....||. .:|       |:....||.:      .|.....||.|......|..|...:|.|:
  Fly   417 -YDEGTRLPYSYD-------TFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQDL 473

  Fly   174 ALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNF----------PFQIAGWGDSGLQQKSTVLRQ 228
            |||.|....:.:..|||||:         :|.:|          ..:.|||   .::.|..:...
  Fly   474 ALLTLDEPFELSHVIRPICV---------TFASFAEKESVTDDVQGKFAGW---NIENKHELQFV 526

  Fly   229 GTISGMSPDECLNRYPTLLVDKDIQICAMGWDGTDTGLGDSGSPLMASVGRGA-----DQFYYLA 288
            ..:| .|...|......:..||   .|......:....||||....:.:...|     ...::|.
  Fly   527 PAVS-KSNSVCRRNLRDIQADK---FCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLF 587

  Fly   289 GITSYGGGPSSYGYGPAVYTKTSSYYEWIKKKINDIAE 326
            |:.|.........:...|.|....:.:.|...:|...|
  Fly   588 GVISNAPNADQCAHSLTVMTNIQHFEDMILNAMNRSVE 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..320	CDD:238113	63/279 (23%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	62/276 (22%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	9/47 (19%)
		Tryp_SPc	371..616	CDD:214473	62/274 (23%)
		Tryp_SPc	371..591	CDD:304450	59/249 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030