Protein Alignment CG12133 and TMPRSS11F

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_997290.2
• Gene: TMPRSS11F / 389208
• HGNCID: 29994
• Length: 438
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 94/339 - (27%)
• Similarity: 135/339 - (39%)
• Gaps: 107/339 - (31%)

  Fly     7 RNMTNDQKSQYRNKLCNINPFAHELVHMVFTCCPMVAGDKLPDSRVCGQSPPSSYIVGGME-AQS 70
            ||:.|.:        |.|        .|..:..|:.|            |..:..||.|.| |..
Human   179 RNLLNSR--------CGI--------RMTSSNMPLPA------------SSSTQRIVQGRETAME 215

  Fly    71 NQFPWTVLL-----GYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFYVARVRLGEHDTEN 130
            .::||...|     |::           |..|||::.::||||||...|               .
Human   216 GEWPWQASLQLIGSGHQ-----------CGASLISNTWLLTAAHCFWKN---------------K 254

  Fly   131 DPDYTWLPN-GAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQIRPICIW 194
            ||. .|:.. ||.|..|| |..:|...:.||.|:.....  |||||::|.:.|:::..::.:|
Human   255 DPT-QWIATFGATITPPA-VKRNVRKIILHENYHRETNE--NDIALVQLSTGVEFSNIVQRVC-- 313

  Fly   195 PGIELSTSSFKNFP---FQIAGWG---DSGLQQKSTVLRQGTISGMSPDECLNRYPTLLVDKDI- 252
                |..||.|..|   ..:.|:|   |.|..|.:  |||..:..:|.|.| ||       ||:
Human   314 ----LPDSSIKLPPKTSVFVTGFGSIVDDGPIQNT--LRQARVETISTDVC-NR-------KDVY 364

  Fly   253 -------QICAMGWDG-TDTGLGDSGSPLMASVGRGADQFYYLAGITSYGGG---PSSYGYGPAV 306
                   .:||...:| .|...||||.||:..    ....:|:.||.|:|..   |..    |.|
Human   365 DGLITPGMLCAGFMEGKIDACKGDSGGPLVYD----NHDIWYIVGIVSWGQSCALPKK----PGV 421

  Fly   307 YTKTSSYYEWIKKK 320
            ||:.:.|.:||..|
Human   422 YTRVTKYRDWIASK 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	82/279 (29%)
TMPRSS11F	NP_997290.2	SEA	59..158	CDD:460188
		Tryp_SPc	206..435	CDD:238113	84/282 (30%)