Protein Alignment CG12133 and PRSS48

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 84/294 - (28%)
• Similarity: 123/294 - (41%)
• Gaps: 67/294 - (22%)

  Fly    52 VCGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDF 116
            ||||...||.:|||.:|.:.::||.|.|.::       .:.:|.|||::.|.:||||||:..
Human    18 VCGQPVYSSRVVGGQDAAAGRWPWQVSLHFD-------HNFICGGSLVSERLILTAAHCIQP--- 72

  Fly   117 YVARVRLGEHDTENDPDYTWLPNGAKIW--------APAHVDIDVDLRVPHEQYYTRNGRHYNDI 173
                              ||......:|        :...|...|...|.|.:|.....    |:
Human    73 ------------------TWTTFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKYQDTTA----DV 115

  Fly   174 ALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPF-QIAGWG---DSGLQQKSTVLRQGTISGM 234
            |||:|.|:|.:|..|.|||: |.:   |......|| .:.|||   :|..:...:.|::..:..:
Human   116 ALLKLSSQVTFTSAILPICL-PSV---TKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPII 176

  Fly   235 SPDECLNRY-------PTL-LVDKDIQICAMGWDG-TDTGLGDSGSPLMASVGRGADQFYYLAGI 290
            ....|...|       |.| .|.|:.:|||..... .|:..||||.||...:    |..:...|:
Human   177 DRQACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHI----DGVWIQTGV 237

  Fly   291 TSYG--GGPSSYGYGPAVYTKTSSYYEWIKKKIN 322
            .|:|  .|.|.    |.|||....|.:||...|:
Human   238 VSWGLECGKSL----PGVYTNVIYYQKWINATIS 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	75/277 (27%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	77/280 (28%)