Protein Alignment CG12133 and OVCH1

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_024304736.1
• Gene: OVCH1 / 341350
• HGNCID: 23080
• Length: 1120
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 91/311 - (29%)
• Similarity: 142/311 - (45%)
• Gaps: 68/311 - (21%)

  Fly    52 VCGQSPP------SSYIVGGMEAQSNQFPWTV---LLG-YEAYTAKQRPSPMCAGSLIASRYVLT 106
            ||| .||      |..|.||.||..:.:||.|   .|| |:           |.|::|...::||
Human   595 VCG-IPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQ-----------CGGAIINPVWILT 647

  Fly   107 AAHCLNV-NDFYVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHY 170
            ||||:.: |:.....:..|:|| .|..:.|.....||     |:       :.||.:.|.:  :.
Human   648 AAHCVQLKNNPLSWTIIAGDHD-RNLKESTEQVRRAK-----HI-------IVHEDFNTLS--YD 697

  Fly   171 NDIALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPFQIAGWG----DSGLQQKSTVLRQGTI 231
            :||||::|.|.::|...:||:|:....|   ..|.:....:.|||    |.||..:   |:|..:
Human   698 SDIALIQLSSPLEYNSVVRPVCLPHSAE---PLFSSEICAVTGWGSISADGGLASR---LQQIQV 756

  Fly   232 SGMSPDECLNRY----PTLLVDKDIQICAMGWDGT---DTGLGDSGSPLMASVGRGADQFYYLAG 289
            ..:..:.|.:.|    |..:.:|  .||| |:..:   |...||||.||:.....|.   :.|.|
Human   757 HVLEREVCEHTYYSAHPGGITEK--MICA-GFAASGEKDFCQGDSGGPLVCRHENGP---FVLYG 815

  Fly   290 ITSYGGG---PSSYGYGPAVYTKTSSYYEWIKKKINDIAEDERKMKYKSVR 337
            |.|:|.|   |    :.|.|:.:...:.:||:.|||..|..:...|.|:::
Human   816 IVSWGAGCVQP----WKPGVFARVMIFLDWIQSKINGPASLQTNNKCKTLK 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	77/273 (28%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	79/276 (29%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001