Protein Alignment CG12133 and Prss22

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001100454.1
• Gene: Prss22 / 302971
• RGDID: 1310880
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 303
• Identity: 84/303 - (27%)
• Similarity: 140/303 - (46%)
• Gaps: 44/303 - (14%)

  Fly    34 MVFTCCPMVAGDKLPDSRVCGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSL 98
            ::.|....|:...:..|..||:....:.:|||.::...|:||.|       :..:..|..|||||
  Rat    22 VLLTSTATVSAANIRGSPDCGKPQQLNRVVGGEDSADAQWPWIV-------SILKNGSHHCAGSL 79

  Fly    99 IASRYVLTAAHCLNVNDFYVARVRLGEHDTENDPDYTWLPNGAKIW--APAHVDIDVDLRVPHEQ 161
            :.:|:|::||||.:.|             .:....|:.|....|:.  .|....:.:...:||.:
  Rat    80 LTNRWVVSAAHCFSSN-------------MDKPSPYSVLLGAWKLGNPGPRSQKVGIASVLPHPR 131

  Fly   162 YYTRNGRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPFQIAGWGDSGLQQKSTVL 226
            |..:.|.| .||||:||:..::::.:|.|||: |  :.|.....|....|||||  .:|....:.
  Rat   132 YSRKEGTH-ADIALVRLERPIQFSERILPICL-P--DSSVHLPPNTNCWIAGWG--SIQDGVPLP 190

  Fly   227 RQGTISGM-----SPDECLNRY----PTLLVDKDIQICAMGWDG-TDTGLGDSGSPLMASVGRGA 281
            |..|:..:     .|:.|.:.|    ....:.:|: :||...:| .|..|||||.|||..|
  Rat   191 RPQTLQKLKVPIIDPELCKSLYWRGAGQEAITEDM-LCAGYLEGKRDACLGDSGGPLMCQV---- 250

  Fly   282 DQFYYLAGITSYGGGPSSYGYGPAVYTKTSSYYEWIKKKINDI 324
            |..:.|.||.|:|.|.:... .|.|||...::..|:::.:..:
  Rat   251 DDHWLLTGIISWGEGCAERN-RPGVYTSLLAHRPWVQRIVQGV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	78/266 (29%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	79/269 (29%)