Protein Alignment CG12133 and HABP2

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 92/335 - (27%)
• Similarity: 145/335 - (43%)
• Gaps: 63/335 - (18%)

  Fly     9 MTNDQ-KSQYRNKLCNINP-FAHELVHMVFTCCPMVAGDKLPDSRVCGQSPPS----SYIVGGME 67
            :|||: |.:|    |:::. .|.::.:...:  |.....|||....||::..:    ..|.||.:
Human   261 VTNDKVKWEY----CDVSACSAQDVAYPEES--PTEPSTKLPGFDSCGKTEIAERKIKRIYGGFK 319

  Fly    68 AQSNQFPWTVLLGYE-AYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFYVARVRLGEHDTEND 131
            :.:.:.||...|... ..|........|.|:||...:|||||||.::...:: :|.||:.|.:.:
Human   320 STAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRHL-KVVLGDQDLKKE 383

  Fly   132 PDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKS-------RVKYTLQIR 189
            ..:.......||:..:|             |..|:...:||||||:||.       ..||   ::
Human   384 EFHEQSFRVEKIFKYSH-------------YNERDEIPHNDIALLKLKPVDGHCALESKY---VK 432

  Fly   190 PICIWPGIELSTSSFKNFP----FQIAGWGDSGLQQKSTVLRQGTISGMSPDECLNR--YPTLLV 248
            .:|:..|         :||    ..|:|||.:...:.|..|....:..::...|.:|  |..::
Human   433 TVCLPDG---------SFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMI- 487

  Fly   249 DKDIQICA--MGWDGTDTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKTS 311
             .|..|||  :...|.||..||||.||...    .|..||:.||.|:|   ...|..|.|||:.:
Human   488 -DDSMICAGNLQKPGQDTCQGDSGGPLTCE----KDGTYYVYGIVSWG---LECGKRPGVYTQVT 544

  Fly   312 SYYEWIKKKI 321
            .:..|||..|
Human   545 KFLNWIKATI 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	75/270 (28%)
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056	6/19 (32%)
		Tryp_SPc	314..553	CDD:238113	78/273 (29%)