DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12133 and F10

DIOPT Version :9

Sequence 1:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	81/282 - (28%)
Similarity:	133/282 - (47%)	Gaps:	51/282 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 IVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFYVARVRLGEH 126
            ||||.|.:..:.||..||     .:.:.....|.|:::...|:|||||||:....:  :||:|:.
  Rat   232 IVGGQECKRGECPWQALL-----FSDEETDGFCGGTILNEFYILTAAHCLHQAKRF--KVRVGDL 289

  Fly   127 DTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQIRPI 191
            :||.:       :|.::   .|   :||:.:.|.::  :...:..|||:||||:.:.:...:.|.
  Rat   290 NTEQE-------DGGEM---VH---EVDMIIKHNKF--QRDTYDFDIAMLRLKTPITFRENVAPA 339

  Fly   192 CI----WPGIELSTSSFKNFPFQIAGWG---DSGLQQKSTVLRQGTISGMSPDECLNRYPTLLVD 249
            |:    |....|.|..    ...::|:|   :.|.|.|  ||:...:..:..:.|  |..|....
  Rat   340 CLPQKDWAEATLMTQK----TGIVSGFGRTHEKGRQSK--VLKMMEVPYVDRNTC--RLSTSFSI 396

  Fly   250 KDIQICAMGWDG--TDTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYG-YGPAVYTKTS 311
            .....|| |:|.  .|...||||.|   .|.|..|. |::.||.|:|.|.:..| ||  :|||.:
  Rat   397 TQNMFCA-GYDAKQEDACQGDSGGP---HVTRFKDT-YFVTGIVSWGEGCARKGKYG--IYTKVT 454

  Fly   312 SYYEWI----KKKINDIAEDER 329
            ::.:||    |.::...:|..|
  Rat   455 AFLKWIDRSMKARVGPTSETPR 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..320	CDD:238113	79/271 (29%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	76/264 (29%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372
		Tryp_SPc	232..462	CDD:238113	78/266 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000