Protein Alignment CG12133 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 83/290 - (28%)
• Similarity: 123/290 - (42%)
• Gaps: 65/290 - (22%)

  Fly    53 CGQSP-----PSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLN 112
            ||.:|     ..|.|:||.|||:..:||.|.|..:.......   :|.|:|:..|:|||||||..
Human    64 CGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVH---VCGGTLVRERWVLTAAHCTK 125

  Fly   113 VNDFYVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPH-----------------E 160
                           ..:||         .:|.......::..|.||                 |
Human   126 ---------------DASDP---------LMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILE 166

  Fly   161 QYYTRNGRHYNDIALLRLKSRVKYTLQIRPICI-WPGIELSTSSFKNFPFQIAGWGDSGLQQKST 224
            .|       .|||||..||..|:|...|:|||: :...::...:.|.|   |:|||.:..:..:|
Human   167 SY-------VNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCF---ISGWGRTKEEGNAT 221

  Fly   225 -VLRQGTISGMSPDECLNRYPTLLVDKDIQICAMGWDGT-DTGLGDSGSPLMASVGRGADQFYYL 287
             :|:...:..:|.:.|.:......:..:...||...||. ||..||||.|||..:..  .:.:::
Human   222 NILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPE--YKRFFV 284

  Fly   288 AGITSYGGGPSSYGYGPAVYTKTSSYYEWI 317
            .||||||.|....|: |.||...|.|.:|:
Human   285 MGITSYGHGCGRRGF-PGVYIGPSFYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	78/274 (28%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	79/276 (29%)