DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12133 and Sp212

DIOPT Version :9

Sequence 1:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	92/301 - (30%)
Similarity:	137/301 - (45%)	Gaps:	78/301 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SRVCG-QSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLN- 112
            |.||| :...:.:||.|.|....|:||...:.::...|.   :..|.||||:|..|::||||::
  Fly   264 SVVCGREGSTTPFIVRGNEFPRGQYPWLSAVYHKEVRAL---AFKCRGSLISSSIVISAAHCVHR 325

  Fly   113 -VNDFYVARVRLGEHDTENDPDYTWLPNGAK-------IWAPAHVDIDVDLRVPHEQYYTRNGRH 169
             ..|..|  |.||.:|.:   ||.  .:||:       :|              |..|.||:
  Fly   326 MTEDRVV--VGLGRYDLD---DYG--EDGAEMRNVMRLLW--------------HPDYNTRS--- 366

  Fly   170 YN--DIALLRLKSRVKYTLQIRPICIWPGIE----LSTSSFKNFPFQIAGWG---DSGLQQKSTV 225
            |:  ||||:.::..|.:...|.|||:|. :|    :||:.|      |||||   ||...|...|
  Fly   367 YSDADIALITIERPVTFNDIIAPICMWT-VEASRTVSTTGF------IAGWGRDEDSSRTQYPRV 424

  Fly   226 LRQGTISGMSPDECLNRY-PTLLVDKDIQICAMGWDGTDTGLGDSGSPLMASVGRGADQFYYLAG 289
            : :..|:  ||..|.:.: .|::.::  .:||...||:...:||||..||...|   |: :.|.|
  Fly   425 V-EAEIA--SPTVCASTWRGTMVTER--SLCAGNRDGSGPCVGDSGGGLMVKQG---DR-WLLRG 480

  Fly   290 ITSYGGGPSSYGYGPA---------VYTKTSSYYEWIKKKI 321
            |.|.|      ..|||         :|...|.:..||.:.|
  Fly   481 IVSAG------ERGPAGTCQLNQYVLYCDLSKHINWISENI 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..320	CDD:238113	87/285 (31%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	85/282 (30%)
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	87/285 (31%)
		Tryp_SPc	277..511	CDD:214473	85/282 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437230
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930