Protein Alignment CG12133 and PRSS33

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_690851.2
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 88/312 - (28%)
• Similarity: 133/312 - (42%)
• Gaps: 82/312 - (26%)

  Fly    43 AGDKLPDSRVCGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTA 107
            ||.:...|..|||...||.||||.:.:..::||..       :.:.|.:.:|.|||||.::||||
Human    18 AGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQA-------SIQHRGAHVCGGSLIAPQWVLTA 75

  Fly   108 AHCLNVNDFYVA-RVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYN 171
            |||......... |||||.           |..|:.  :|..:.:.| .||.....|:.:|.. .
Human    76 AHCFPRRALPAEYRVRLGA-----------LRLGST--SPRTLSVPV-RRVLLPPDYSEDGAR-G 125

  Fly   172 DIALLRLKSRVKYTLQIRPICI-WPGIELSTSSFKNFPFQIAGWGDSGLQQKSTVLRQGT----- 230
            |:|||:|:..|..:.:::|:|: .||......:    |.::.|||.         ||.|.
Human   126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGT----PCRVTGWGS---------LRPGVPLPEW 177

  Fly   231 --ISGMSPDECLNRYPTL---------LVDKDI----------QICAMGWDG-TDTGLGDSGSPL 273
              :.|:       |.|.|         .|..|:          .:||....| .|...||||.||
Human   178 RPLQGV-------RVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPL 235

  Fly   274 MASVGRGADQFYYLAGITSYGGG---PSSYGYGPAVYTKTSSYYEWIKKKIN 322
             ..:..|:   :.|.|:.|:|.|   |:.    |.|||..::|..||:.:::
Human   236 -TCLQSGS---WVLVGVVSWGKGCALPNR----PGVYTSVATYSPWIQARVS 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	78/286 (27%)
PRSS33	NP_690851.2	Tryp_SPc	37..275	CDD:238113	79/287 (28%)