DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12133 and CG30187

DIOPT Version :9

Sequence 1:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	88/287 - (30%)
Similarity:	122/287 - (42%)	Gaps:	49/287 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 RVCGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVND 115
            ::||.: .:..|.||..|......|..       ....|...:|.|:||..|:|||||||:...|
  Fly    26 QICGIN-IALKITGGHNAAFQNSVWMA-------AVHNRTHFICGGTLIHKRFVLTAAHCIVDQD 82

  Fly   116 FYVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKS 180
              |..|.||.::..:..|..                ||...|.|..:..| ..:.|||.||:|.|
  Fly    83 --VQSVSLGAYNKSDPADRK----------------DVITAVVHSSFDVR-ASYENDIGLLKLSS 128

  Fly   181 RVKYTLQIRPICIWPGIELSTSSFKNFPFQIAGWGDSGLQQKSTVLRQGTISGMSPDEC---LNR 242
            .|.:...||||||.....::........|:..|||.....:.|.:|:...::.:..:||   |:.
  Fly   129 DVIFNALIRPICIVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQTIILNHLDREECYMELSV 193

  Fly   243 YPTLLVDKDIQICAMGWDGTDTGLGDSGSPL-----MASVGRGADQFYYLAGITSYGGGPSSYGY 302
            ||:     :.|||| |....||..||||.||     :..:|....||    ||.|.|.....
  Fly   194 YPS-----EKQICA-GVPSGDTCGGDSGGPLTNDVFIQGIGNREVQF----GIISVGKTSCD--- 245

  Fly   303 GPAVYTKTSSYYEWIKKKINDIA-EDE 328
            |..|||...|:.:|||..|..:: |||
  Fly   246 GQGVYTDLMSFADWIKMTIERLSIEDE 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..320	CDD:238113	82/265 (31%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	79/262 (30%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	79/263 (30%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010