Protein Alignment CG12133 and PRSS55

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 94/347 - (27%)
• Similarity: 141/347 - (40%)
• Gaps: 94/347 - (27%)

  Fly    33 HMVFTCCPMVAGDKLPDSRVCGQSPPS-------------SYIVGGMEAQSNQFPWTVLLGYEAY 84
            |.:.|.|       .|.|......||.             |.|.|||||:..:|||.|
Human    57 HWMLTKC-------FPFSFPLSFFPPECGDRSIFEGRTRYSRITGGMEAEVGEFPWQV------- 107

  Fly    85 TAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFYVAR--VRLGEHDTENDPDYTWLPNGAKIWAPA 147
            :.:.|..|.|.||::...::|||||||...:.:...  |.||.:|               :.:|:
Human   108 SIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTND---------------LTSPS 157

  Fly   148 HVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPFQ-- 210
            ....:|...:.|:.:  :.....||||||.|.|.:|......|||:              |.|
Human   158 MEIKEVASIILHKDF--KRANMDNDIALLLLASPIKLDDLKVPICL--------------PTQPG 206

  Fly   211 --------IAGWGDSGLQQKSTV---LRQGTISGMSPDECLNRYPTLLVDKDIQICAMGW--DGT 262
                    :||||.:....|::|   |.:..:..|..:||...:|.|..:   .:|| |:  :..
Human   207 PATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPKLTKN---MLCA-GYKNESY 267

  Fly   263 DTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYG--YGPAVYTKTSSYYEWIKKKINDI- 324
            |...||||.||:.:...|  :.:|..||.|:|   .|.|  ..|.:||...:|..|| :|:..:
Human   268 DACKGDSGGPLVCTPEPG--EKWYQVGIISWG---KSCGEKNTPGIYTSLVNYNLWI-EKVTQLE 326

  Fly   325 -----AEDER-KMKYKSVRIPI 340
                 ||..| .:|.|.:..|:
Human   327 GRPFNAEKRRTSVKQKPMGSPV 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	77/273 (28%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	79/277 (29%)