DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12133 and C1s

DIOPT Version :9

Sequence 1:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_620255.2	Gene:	C1s / 192262	RGDID:	619983	Length:	694	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	90/315 - (28%)
Similarity:	124/315 - (39%)	Gaps:	83/315 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GDKLPDS-RVCGQSPPSSY-----IVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASR 102
            |.:||.. .||| .|...:     |.||...:...|||.|..          .||...|:||...
  Rat   421 GVELPKCIPVCG-VPTEPFKVQQRIFGGYSTKIQSFPWQVYF----------ESPRGGGALIDEY 474

  Fly   103 YVLTAAHCLNVND---FYVARVRLGEHDTENDPDYTWLPNGAKI----------WAPAHVDIDVD 154
            :||||||.:..|.   .||....|         ....|.|..::          |..   :.|::
  Rat   475 WVLTAAHVVEGNSDPVMYVGSTLL---------KIERLRNAQRLITERVIIHPSWKQ---EDDLN 527

  Fly   155 LRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPFQ-----IAGW 214
            .|...:          |||||::||..||....:.|||: |    .|||..| |.:     |:||
  Rat   528 TRTNFD----------NDIALVQLKDPVKMGPTVAPICL-P----ETSSDYN-PSEGDLGLISGW 576

  Fly   215 GDSGLQQKSTVLRQGTISGMSPDEC-----------LNRYPTLLVDKDIQICAMGWDGTDTGLGD 268
            |.:..:.....||...:...|.::|           .|.|    |..|..||| |..|.|:..||
  Rat   577 GRTENRTNVIQLRGAKLPITSLEKCQQVKVENPKARSNDY----VFTDNMICA-GEKGVDSCEGD 636

  Fly   269 SGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKTSSYYEWIKKKIND 323
            ||......|....|..:|:||:.|:|....:||    :|||..:|.:||.|.:.:
  Rat   637 SGGAFALPVPNVKDPKFYVAGLVSWGKKCGTYG----IYTKVKNYVDWILKTMQE 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..320	CDD:238113	82/286 (29%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	80/283 (28%)
C1s	NP_620255.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:405372
		CUB	181..293	CDD:395345
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056	3/6 (50%)
		Tryp_SPc	443..681	CDD:214473	80/284 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000