Protein Alignment CG12133 and C1s

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_620255.2
• Gene: C1s / 192262
• RGDID: 619983
• Length: 694
• Species: Rattus norvegicus
• Alignment Length: 315
• Identity: 90/315 - (28%)
• Similarity: 124/315 - (39%)
• Gaps: 83/315 - (26%)

  Fly    44 GDKLPDS-RVCGQSPPSSY-----IVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASR 102
            |.:||.. .||| .|...:     |.||...:...|||.|..          .||...|:||...
  Rat   421 GVELPKCIPVCG-VPTEPFKVQQRIFGGYSTKIQSFPWQVYF----------ESPRGGGALIDEY 474

  Fly   103 YVLTAAHCLNVND---FYVARVRLGEHDTENDPDYTWLPNGAKI----------WAPAHVDIDVD 154
            :||||||.:..|.   .||....|         ....|.|..::          |..   :.|::
  Rat   475 WVLTAAHVVEGNSDPVMYVGSTLL---------KIERLRNAQRLITERVIIHPSWKQ---EDDLN 527

  Fly   155 LRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPFQ-----IAGW 214
            .|...:          |||||::||..||....:.|||: |    .|||..| |.:     |:||
  Rat   528 TRTNFD----------NDIALVQLKDPVKMGPTVAPICL-P----ETSSDYN-PSEGDLGLISGW 576

  Fly   215 GDSGLQQKSTVLRQGTISGMSPDEC-----------LNRYPTLLVDKDIQICAMGWDGTDTGLGD 268
            |.:..:.....||...:...|.::|           .|.|    |..|..||| |..|.|:..||
  Rat   577 GRTENRTNVIQLRGAKLPITSLEKCQQVKVENPKARSNDY----VFTDNMICA-GEKGVDSCEGD 636

  Fly   269 SGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKTSSYYEWIKKKIND 323
            ||......|....|..:|:||:.|:|....:||    :|||..:|.:||.|.:.:
  Rat   637 SGGAFALPVPNVKDPKFYVAGLVSWGKKCGTYG----IYTKVKNYVDWILKTMQE 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	80/283 (28%)
C1s	NP_620255.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:464251
		CUB	181..293	CDD:395345
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056	3/6 (50%)
		Tryp_SPc	443..681	CDD:214473	80/284 (28%)