Protein Alignment CG12133 and Tmprss15

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_032967.1
• Gene: Tmprss15 / 19146
• MGIID: 1197523
• Length: 1069
• Species: Mus musculus
• Alignment Length: 302
• Identity: 93/302 - (30%)
• Similarity: 140/302 - (46%)
• Gaps: 63/302 - (20%)

  Fly    34 MVFTCCPMVAGDKLPDSRVCGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSL 98
            ::..|.....|:|....:|      |..||||.:||:..:||.|.| |....:..|  .:|..||
Mouse   808 ILLQCNHKSCGEKKVTQKV------SPKIVGGSDAQAGAWPWVVAL-YHRDRSTDR--LLCGASL 863

  Fly    99 IASRYVLTAAHCLNVNDFYVAR--VRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRV--PH 159
            ::|.::::||||:...:....|  ..||.|...|            :.:|..|...||..|  ||
Mouse   864 VSSDWLVSAAHCVYRRNLDPTRWTAVLGLHMQSN------------LTSPQVVRRVVDQIVINPH 916

  Fly   160 EQYYTRNGRHYNDIALLRLKSRVKYTLQIRPICI-------WPGIELSTSSFKNFPFQIAGWGDS 217
               |.|. |..||||::.|:.:|.||..|:|||:       .||...|          |||||..
Mouse   917 ---YDRR-RKVNDIAMMHLEFKVNYTDYIQPICLPEENQIFIPGRTCS----------IAGWGYD 967

  Fly   218 GLQQKST--VLRQGTISGMSPDECLNRYPTLLVDKDIQICAMGWD--GTDTGLGDSGSPLMASVG 278
            .:...||  ||::..:..:|.::|..:.|...:.:.: ||| |::  |.|:..||||.|||..
Mouse   968 KINAGSTVDVLKEADVPLISNEKCQQQLPEYNITESM-ICA-GYEEGGIDSCQGDSGGPLMCQ-- 1028

  Fly   279 RGADQFYYLAGITSYG---GGPSSYGYGPAVYTKTSSYYEWI 317
              .:..::|.|:||:|   ..|:.    |.||.:.|.:.|||
Mouse  1029 --ENNRWFLVGVTSFGVQCALPNH----PGVYVRVSQFIEWI 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	86/272 (32%)
Tmprss15	NP_032967.1	SEA	53..154	CDD:214554
		LDLa	228..261	CDD:197566
		CUB	270..376	CDD:412131
		MAM	392..548	CDD:459878
		CUB	569..676	CDD:395345
		LDLa	688..722	CDD:238060
		SR	723..816	CDD:214555	1/7 (14%)
		Tryp_SPc	830..1066	CDD:238113	88/274 (32%)