Protein Alignment CG12133 and Hpn

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001263198.1
• Gene: Hpn / 15451
• MGIID: 1196620
• Length: 445
• Species: Mus musculus
• Alignment Length: 313
• Identity: 88/313 - (28%)
• Similarity: 138/313 - (44%)
• Gaps: 41/313 - (13%)

  Fly    26 PFAHELVHMVFTC-CPMVAGDKLPDS-RVCGQSP-PSSYIVGGMEAQSNQFPWTVLLGYEAYTAK 87
            |.|..|:.::..| ||  .|..|..: :.||:.. |...||||.::...::||.|.|.|:.
Mouse   154 PLAQRLLDVISVCDCP--RGRFLTATCQDCGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDG---- 212

  Fly    88 QRPSPMCAGSLIASRYVLTAAHCLNVNDFYVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDID 152
               :.:|.|||::..:|||||||....:..::|.|:             ........:|..|.:.
Mouse   213 ---THLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV-------------FAGAVARTSPHAVQLG 261

  Fly   153 VDLRVPHEQYYTRN----GRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPFQIAG 213
            |...:.|..|....    ..:.|||||:.|.|.:..|..|:|:|: |....:....|  ...:.|
Mouse   262 VQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCL-PAAGQALVDGK--VCTVTG 323

  Fly   214 WGDSGLQ-QKSTVLRQGTISGMSPDECLNR--YPTLLVDKDIQICAMGW--DGTDTGLGDSGSPL 273
            ||::... |::.||::..:..:|.:.|.:.  |...:..|  ..|| |:  .|.|...||||.|.
Mouse   324 WGNTQFYGQQAMVLQEARVPIISNEVCNSPDFYGNQIKPK--MFCA-GYPEGGIDACQGDSGGPF 385

  Fly   274 MASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKTSSYYEWIKKKINDIAE 326
            :..........:.|.||.|:|.| .:....|.||||.:.:.|||.|.|...:|
Mouse   386 VCEDSISGTSRWRLCGIVSWGTG-CALARKPGVYTKVTDFREWIFKAIKTHSE 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	72/263 (27%)
Hpn	NP_001263198.1	Hepsin-SRCR	79..187	CDD:462736	10/34 (29%)
		Tryp_SPc	191..428	CDD:238113	72/263 (27%)