Protein Alignment CG12133 and CTRL

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001898.1
• Gene: CTRL / 1506
• HGNCID: 2524
• Length: 264
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 83/274 - (30%)
• Similarity: 122/274 - (44%)
• Gaps: 54/274 - (19%)

  Fly    59 SSYIVGGMEAQSNQFPWTVLL----GYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVN---DF 116
            |..||.|..|....:||.|.|    |:.          .|.||||:..:|:||||| ||:   .|
Human    31 SQRIVNGENAVLGSWPWQVSLQDSSGFH----------FCGGSLISQSWVVTAAHC-NVSPGRHF 84

  Fly   117 YVARVRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQY--YTRNGRHYNDIALLRLK 179
            .|    |||:|..::.:            |..| :.|...:.|..:  .|.|    ||:.||:|.
Human    85 VV----LGEYDRSSNAE------------PLQV-LSVSRAITHPSWNSTTMN----NDVTLLKLA 128

  Fly   180 SRVKYTLQIRPICIWPGIELSTSSFKNFPFQIAGWGD-SGLQQKSTV-LRQGTISGMSPDECLNR 242
            |..:||.:|.|:|:....|..|   :.......|||. ||:...:.. |:|..:..::.::|...
Human   129 SPAQYTTRISPVCLASSNEALT---EGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQY 190

  Fly   243 YPTLLVDKDIQICAMGWDGTDTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVY 307
            :.:.:.|.  .||| |..|..:..||||.||:...|    ..:.|.||.|:|....:. ..||||
Human   191 WGSSITDS--MICA-GGAGASSCQGDSGGPLVCQKG----NTWVLIGIVSWGTKNCNV-RAPAVY 247

  Fly   308 TKTSSYYEWIKKKI 321
            |:.|.:..||.:.|
Human   248 TRVSKFSTWINQVI 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	79/265 (30%)
CTRL	NP_001898.1	Tryp_SPc	34..260	CDD:238113	81/268 (30%)