Protein Alignment CG12133 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 84/316 - (26%)
• Similarity: 129/316 - (40%)
• Gaps: 71/316 - (22%)

  Fly    20 KLCNINPFAHELVHMVFTCCPMVAGDKLPDSRVCGQSPPSSYIVGGMEAQSNQFPWTVLLGYEAY 84
            ||..|:..|.|:  :...||    |.::.:|.:.|..     ||.|..:....:||...:.::.
Human   154 KLMEISKAASEM--LTNNCC----GRQVANSIITGNK-----IVNGKSSLEGAWPWQASMQWKG- 206

  Fly    85 TAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFYVARVRLGEHDTENDPDYTWLPNGAKIWAPAHV 149
                  ...|..|||:||::|:||||....:              |..|  |..|...:....::
Human   207 ------RHYCGASLISSRWLLSAAHCFAKKN--------------NSKD--WTVNFGIVVNKPYM 249

  Fly   150 DIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQIRPICIWPGIELSTSSFKNFPFQIAGW 214
            ...|...:.||. |:..|.| :||||::|...|.:|..||.||: |..::..|  :|....:.||
Human   250 TRKVQNIIFHEN-YSSPGLH-DDIALVQLAEEVSFTEYIRKICL-PEAKMKLS--ENDNVVVTGW 309

  Fly   215 GDSGLQQKSTVLRQGTISGMSPDECLNRYPTLLVDKDIQICAMGWDG--TDTGL----------- 266
            |        |:...|:...:..::.|.     ::|..|...:..:.|  |||.|
Human   310 G--------TLYMNGSFPVILQEDFLK-----IIDNKICNASYAYSGFVTDTMLCAGFMSGEADA 361

  Fly   267 --GDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKTSSYYEWIKKK 320
              .|||.||.....|   ..::|.||.|:|.|..... .|.|||:.:||..||..|
Human   362 CQNDSGGPLAYPDSR---NIWHLVGIVSWGDGCGKKN-KPGVYTRVTSYRNWITSK 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	71/269 (26%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188
		Tryp_SPc	185..413	CDD:238113	73/272 (27%)