DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pal1 and pghm-1

DIOPT Version :9

Sequence 1:	NP_001137630.2	Gene:	Pal1 / 36033	FlyBaseID:	FBgn0283510	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_490898.1	Gene:	pghm-1 / 171746	WormBaseID:	WBGene00022144	Length:	324	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	61/298 - (20%)
Similarity:	86/298 - (28%)	Gaps:	131/298 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 LVPEL-QLLCA----ADRENGRVQCF--LSSNGTFHSQYHNQLIG------DRLF---------- 332
            :|||. ..||.    :|:|| .:..|  |::.||.|   |..|.|      |.|.
Worm    32 VVPEADSYLCTSLELSDQEN-YLTGFKALTTKGTAH---HILLFGCEEPGSDELVWDCGEMNKPD 92

  Fly   333 -SMAYTPAAGGQLVI-----VNGPTAELGIHPEHYNEVHGFVLSMRSKQLVSKFGPNNLQFQNPH 391
             .|...|..|.:..|     ::.|..||                                   |.
Worm    93 DEMPRAPTCGSKPAILYAWALDAPPLEL-----------------------------------PQ 122

  Fly   392 DVA--VTADGNEIYVAELNPMRIHKFVHRSLAKPMSLSASKDSRDSAISQAVGGDQVPAVAVHHP 454
            ||.  |..|.|..::.    |::| ::|           ||...|..           .:.:.|.
Worm   123 DVGFRVGGDSNIRHLV----MQVH-YMH-----------SKQEPDET-----------GLEITHT 160

  Fly   455 SGKAILVASLMLLFAGSTFALALIFARRRK-----RGCL--------PFGARGRRH-------AW 499
            ......:|:.|||..|.|..       |.|     ..|:        ||..|...|       .|
Worm   161 EEPQPKLAATMLLVTGGTLP-------RNKTESFETACMIEEDVVMHPFAYRTHTHRHGKEVSGW 218

  Fly   500 ------EKSDGFKLGGLLDRD-RNGFEKLDQQASDEEQ 530
                  :..|.:||.|..|.. ...|..::.||...:|
Worm   219 LVKEDQKHEDHWKLIGRRDPQLAQMFVPVEDQAMTIQQ 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pal1	NP_001137630.2	NHL_PAL_like	97..416	CDD:271328	33/155 (21%)
		NHL repeat	111..172	CDD:271328
		NHL repeat	178..220	CDD:271328
		NHL repeat	230..267	CDD:271328
		NHL repeat	283..321	CDD:271328	13/36 (36%)
		NHL repeat	330..382	CDD:271328	8/67 (12%)
		NHL repeat	388..415	CDD:271328	8/28 (29%)
pghm-1	NP_490898.1	Cu2_monooxygen	27..145	CDD:279429	33/156 (21%)
pghm-1	NP_490898.1	Cu2_monoox_C	167..313	CDD:281675	23/97 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002923
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910