Protein Alignment Mef2 and SMP1

DIOPT Version :10

• Sequence 1: NP_001260842.1
• Gene: Mef2 / 36032
• FlyBaseID: FBgn0011656
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_009741.3
• Gene: SMP1 / 852480
• SGDID: S000000386
• Length: 452
• Species: Saccharomyces cerevisiae
• Alignment Length: 477
• Identity: 110/477 - (23%)
• Similarity: 166/477 - (34%)
• Gaps: 122/477 - (25%)

  Fly     1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRV 65
            |||:||:|..|.|:|||.|||.|||.|:.|||:||||||..:||:||..|:|..|:|:|.||..:
Yeast     1 MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSVDMSNL 65

  Fly    66 LLKYTEYNE-PHESLTNKNIIEKENKNGVMSPDSPEAETDYTLTPRTEAKYNK------------ 117
            |..:....: ||      ||||            |....||...||......|
Yeast    66 LNVHQNNTDLPH------NIIE------------PSDYGDYVKKPRVVLNERKRRRRRATVLQPA 112

  Fly   118 -------IDEEFQNMMQRNQMAIGGAGAPRQLPNSSYTLPVSVPV-------------------- 155
                   :..:..:.:|.|    |...|| ...|.:....||.|:
Yeast   113 SHSGSCTVSSQDSSSVQNN----GNLSAP-LASNDAGNAGVSTPLVHCHGAISRSGSNHSDCARN 172

  Fly   156 -------------PGSYGDNLLQASPQMSHT-------NISPRPSSSETDSVYPSGSMLEMSNGY 200
                         .||:..|..:.|....|.       |...:....:|..:....:.....|.|
Yeast   173 SADYQMLQGGLNSGGSFHANDYKESVDQQHVANEAIHRNFMNKRIRPDTHLLLSESNHSNYHNFY 237

  Fly   201 PHSHSPLVGSPSPGPSPGIAHHLSIKQQSPGSQNGRASNLRVVIPPTIAPIPPNMSAPDDVGYAD 265
            |   ||....|.|.....:..::      |..|    |....|||....|:....:...|   ::
Yeast   238 P---SPYENLPKPSLPASLVGNI------PSFQ----SQFVQVIPANSNPMGKGFNGTGD---SE 286

  Fly   266 QRQSQTSLNTPVV---TLQTPIPALTSYSFGAQDFSSSGVMNSADIMSLNTWHQGLVPHSSLSHL 327
            ..:::..::..|.   ||:.|.|.........|..|:.|.::....:.||      :|.::....
Yeast   287 SFEAKQKIHPTVAISNTLEGPAPVQAMVHHLHQLNSNRGKLSGKPYLKLN------IPKATNDAC 345

  Fly   328 AVSNSTPPPATSPVSIKVKAEPQSPPRDLSASGHQQNSNGSTGSGGSSSSTSSNASGGAGGGGAV 392
            ..|.:......||     |.:.|:.|..:.||......:.|...|..::........|..|.
Yeast   346 QRSPAMYSGTASP-----KTDVQATPNQMLASNMSSPLSRSKFLGFKNNDMDDLYHNGRCGS--- 402

  Fly   393 SAANVITHLNNVSVLAGGPSGQ 414
                  |::||.:.....|.|:
Yeast   403 ------TYVNNKTFFLKPPIGR 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	ARG80	1..>203	CDD:227400	70/261 (27%)
		MADS_MEF2_like	2..78	CDD:238165	40/76 (53%)
SMP1	NP_009741.3	MADS_MEF2_like	2..74	CDD:238165	38/71 (54%)
		ARG80	130..452	CDD:227400	58/330 (18%)