DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mef2 and FLC

DIOPT Version :9

Sequence 1:	NP_001260842.1	Gene:	Mef2 / 36032	FlyBaseID:	FBgn0011656	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_196576.1	Gene:	FLC / 830878	AraportID:	AT5G10140	Length:	196	Species:	Arabidopsis thaliana

Alignment Length:	194	Identity:	55/194 - (28%)
Similarity:	94/194 - (48%)	Gaps:	39/194 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTD-MDR 64
            |||||::|.||.::.:|||||:||:.|:::||.:||||||..:||::.|:|.|||.::|.| :.:
plant     1 MGRKKLEIKRIENKSSRQVTFSKRRNGLIEKARQLSVLCDASVALLVVSASGKLYSFSSGDNLVK 65

  Fly    65 VLLKY-----------------TEYNEPHE--SLTNKNIIEKENKNG-----VMSPDSPEAETDY 105
            :|.:|                 ..|...:|  .|.:..::....||.     |...:..|.....
plant    66 ILDRYGKQHADDLKALDHQSKALNYGSHYELLELVDSKLVGSNVKNVSIDALVQLEEHLETALSV 130

  Fly   106 TLTPRTEAKYNKID--EEFQNMMQRNQMAIGG-------AGAPRQLPNS-----SYTLPVSVPV 155
            |...:||.....::  :|.:.|::.....:..       .||..::..|     |..|||::|:
plant   131 TRAKKTELMLKLVENLKEKEKMLKEENQVLASQMENNHHVGAEAEMEMSPAGQISDNLPVTLPL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	MADS_MEF2_like	2..78	CDD:238165	36/95 (38%)
Mef2	NP_001260842.1	HJURP_C	95..155	CDD:289143	13/73 (18%)
FLC	NP_196576.1	MADS_MEF2_like	2..78	CDD:238165	34/75 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I3346
eggNOG	1	0.900	-	-		E1_COG5068
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000108
OrthoInspector	1	1.000	-	-		otm2406
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X116
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810