DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mef2 and SEP2

DIOPT Version :9

Sequence 1:	NP_001260842.1	Gene:	Mef2 / 36032	FlyBaseID:	FBgn0011656	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_186880.1	Gene:	SEP2 / 821151	AraportID:	AT3G02310	Length:	250	Species:	Arabidopsis thaliana

Alignment Length:	235	Identity:	66/235 - (28%)
Similarity:	106/235 - (45%)	Gaps:	61/235 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYAST-DMDR 64
            |||.::::.||.::.||||||.||:.|::|||||||||||.|::||:||:..|||::.|| :|.:
plant     1 MGRGRVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEVSLIVFSNRGKLYEFCSTSNMLK 65

  Fly    65 VLLKYTEYNEPHESLTNKNIIEKENKNGVMSPDSPEAETDYTLTPRTEAKYNKIDEEFQNMMQRN 129
            .|.:|.:.:.....:.||...|.||                     :..:|.|:...::|:.::.
plant    66 TLERYQKCSYGSIEVNNKPAKELEN---------------------SYREYLKLKGRYENLQRQQ 109

  Fly   130 QMAIGGAGAP----------RQLPNS---------SYTLPVSVPVPGSYGDNLLQASPQMS---- 171
            :..:|....|          |||..|         .|.|.....:.|. ...||.|:..:|
plant   110 RNLLGEDLGPLNSKELEQLERQLDGSLKQVRCIKTQYMLDQLSDLQGK-EHILLDANRALSMKLE 173

  Fly   172 ------HTNISPRPSSSETDSVYPSGSMLEMSNGYPHSHS 205
                  |.:|.         ..:..|....::.|:|.:||
plant   174 DMIGVRHHHIG---------GGWEGGDQQNIAYGHPQAHS 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	MADS_MEF2_like	2..78	CDD:238165	37/76 (49%)
Mef2	NP_001260842.1	HJURP_C	95..155	CDD:289143	11/78 (14%)
SEP2	NP_186880.1	MADS_MEF2_like	2..77	CDD:238165	37/74 (50%)
SEP2	NP_186880.1	K-box	84..173	CDD:396188	19/110 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I3346
eggNOG	1	0.900	-	-		E1_COG5068
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000108
OrthoInspector	1	1.000	-	-		otm2406
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X116
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.810