Protein Alignment Mef2 and mef2cb

DIOPT Version :10

• Sequence 1: NP_001260842.1
• Gene: Mef2 / 36032
• FlyBaseID: FBgn0011656
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_009300032.1
• Gene: mef2cb / 798771
• ZFINID: ZDB-GENE-040901-7
• Length: 483
• Species: Danio rerio
• Alignment Length: 581
• Identity: 204/581 - (35%)
• Similarity: 276/581 - (47%)
• Gaps: 170/581 - (29%)

  Fly     1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRV 65
            ||||||||:||.|||||||||.|||||:||||||||||||||||||||:|:|||:||||||||:|
Zfish     1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKV 65

  Fly    66 LLKYTEYNEPHESLTNKNIIEKENKNGVMSPDSPEAETDYTL--TPRTEAKYNKIDEEFQ-NMMQ 127
            |||||||||||||.||.:|:|...|.|:...|||:.:.|.::  :|.::.||.:|:::.. :|:.
Zfish    66 LLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESKDKYREINDDIDLHMIS 130

  Fly   128 RNQMAIGGAGAPRQLPNSSY--TLPVSVPV-PGSYGDNLL----------QASPQMSHTNISPRP 179
            |.::.        .:|:|:|  |:||:..: ||::  |||          ..||.::|     ||
Zfish   131 RQRIC--------AVPSSTYDMTIPVNNQIYPGNH--NLLPLAHHGLQRNSMSPGVTH-----RP 180

  Fly   180 SSS----ETD-------SVYPSGSMLEMSNGY-PHSHSP--LVGSPSPGPSPGIAHHLSIKQQSP 230
            .|:    .||       |....|......||| .|.:||  ||.      |.|:...:..|...|
Zfish   181 PSAGGLMGTDLSTGAGTSAGKDGIPTYYRNGYGNHRNSPGLLVS------SGGMNKSMQAKSPPP 239

  Fly   231 GS--QNGRASNLRVVIPPTIAPIPPNMSAPDDVGYADQR----QSQTSLNTPVVTLQTP-IPAL- 287
            .:  .|.|..:|||:|||......|::|...|: ..:||    ||..||.||||::.|| :|..
Zfish   240 VNLGMNSRKPDLRVLIPPGAKNNMPSISEDVDL-LLNQRINNSQSAQSLATPVVSVATPTLPGQG 303

  Fly   288 -------------TSYSFGAQDFSSSGVMNSADIM---SLNTWHQGLV---PHSSL--------S 325
                         |.||..:.|.||....|||:.:   |::.|.|..:   .||:|        |
Zfish   304 MGGYPSAISTSYGTEYSLSSADLSSISGFNSANTLHLGSMSGWQQHQIQNMQHSALSQLGNCSSS 368

  Fly   326 HLAVSNSTPPPATSPVSIKVKAEPQSPPRDLSASGHQQNSNGSTGSGGSSSSTSSNASGGAGGGG 390
            ||...::...|:|.  |:.:|:||.|||||.|                     ||...||.|
Zfish   369 HLCQGSNLSLPSTQ--SLHIKSEPVSPPRDRS---------------------SSTTPGGYG--- 407

  Fly   391 AVSAANVITHLNNVSVLAGGPSGQGGGGGGGGSNGNVEQATNLSVLSHAQQHHLGMPNSRPSSTG 455
                 .:.:|..:     .||:.||....|         .:....||.....|.|
Zfish   408 -----QLPSHQQH-----QGPTSQGRQDSG---------RSPADSLSSCGSSHEG---------- 443

  Fly   456 HITPTPGAPSSDQDVRLAAVAVQQQQQQPHQQQQLG-------DYDAPNHKRPRISGGWGT 509
                      ||:|           :.:|.....||       |.|:|:.||.|:|.||.|
Zfish   444 ----------SDRD-----------EHRPDFHSPLGLGRPGLDDQDSPSIKRIRLSEGWAT 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	ARG80	1..>203	CDD:227400	110/229 (48%)
		MADS_MEF2_like	2..78	CDD:238165	67/75 (89%)
mef2cb	XP_009300032.1	MADS_MEF2_like	2..78	CDD:238165	67/75 (89%)