Protein Alignment Mef2 and mef2b

DIOPT Version :10

• Sequence 1: NP_001260842.1
• Gene: Mef2 / 36032
• FlyBaseID: FBgn0011656
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_073792680.1
• Gene: mef2b / 558073
• ZFINID: ZDB-GENE-050208-357
• Length: 431
• Species: Danio rerio
• Alignment Length: 557
• Identity: 172/557 - (30%)
• Similarity: 238/557 - (42%)
• Gaps: 178/557 - (31%)

  Fly     1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRV 65
            |||||||||||.|:|||||||.|||||:||||||||||||||||||||:|:|:|:||||||||:|
Zfish     1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNRLFQYASTDMDKV 65

  Fly    66 LLKYTEYNEPHESLTNKNIIEKENKNGVMSPDSPEAETDYTLTPRTEAKYNKIDEEFQNMMQRNQ 130
            |||||||:|||||.||.:|:|...:.| :..:|.|.:.:..:|...| ||:.
Zfish    66 LLKYTEYSEPHESRTNTDILETLRRKG-LGLESSEIDPEDGVTMGAE-KYHD------------- 115

  Fly   131 MAIGGAGAPRQLPNSSYTLPVSVPVPGSYGDNLLQASPQMSHTNISPRPSSSETDSVYPSGSMLE 195
                  |....|....|                  .:|.:.|:.:.  .:|:|
Zfish   116 ------GMDLSLARQRY------------------YAPSLLHSEVI--NTSAE------------ 142

  Fly   196 MSNGYPHSHSPLVG---SPSPGPSPGIAHHLSIKQQSPGSQNGRASNLRVVIPPTIAPIPPNMSA 257
              |||.:|.:|.:|   :||..|       |..:   |||....::|..           |.:..
Zfish   143 --NGYINSSNPNLGAHRTPSYKP-------LCTR---PGSTGTVSANSH-----------PALMG 184

  Fly   258 PDDVGYADQRQSQTSLNTPVVTLQTPIPALTSYSFGAQDFSSSGVMNSADIMSLNTWHQGLVPHS 322
            |    :||     |:|                |:    |...:|:..|            :.||.
Zfish   185 P----HAD-----TNL----------------YN----DIGDTGLGYS------------MFPHG 208

  Fly   323 SLSHLAVSNSTPPPAT-SPVSIKVKAEP--------------QSPPR----DLSASGHQQNSNGS 368
            |||. |:...||||.. |....:|:|..              :|..|    .:.|.||.. :.|.
Zfish   209 SLSR-ALEMKTPPPLNMSSDGRRVEAHAGLCGTRSSLANAVRESTKRALYQSMHAGGHMM-AMGK 271

  Fly   369 TG--SGGSSSSTSSNASGGAGGGGAVSAANV---ITHLN-NVSVLAGGPSGQGGGGGGGGSNGNV 427
            ||  ..|.:.|.|..:..|...|...|:.|.   :||.: :.|:::.|.:       .|||....
Zfish   272 TGLLGHGLNYSPSEYSHPGYTVGFQRSSMNTWQPLTHQDAHQSMISPGMA-------SGGSCSYP 329

  Fly   428 EQATNLSVLSHAQQHHLGMPNSRPSSTGHITPTP-----------------GAPSSDQDVRLAAV 475
            .|:::.|..||... :|.:.:.|.|....|:|||                 ..|.||:...|...
Zfish   330 SQSSSPSSPSHPSL-NLSIKSERTSPVHMISPTPPSHHMLQHSPIAEPKSSSCPPSDEYADLQRE 393

  Fly   476 AVQQ-----QQQQPHQQQQLGDYDAPNHKRPRISGGW 507
            ..|:     |||.|::... ....:||.|:..||.||
Zfish   394 EAQKSSFSGQQQGPNRDPP-ETKSSPNPKQQDISNGW 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	ARG80	1..>203	CDD:227400	89/201 (44%)
		MADS_MEF2_like	2..78	CDD:238165	65/75 (87%)
mef2b	XP_073792680.1	None