Protein Alignment Mef2 and Srf

DIOPT Version :10

• Sequence 1: NP_001260842.1
• Gene: Mef2 / 36032
• FlyBaseID: FBgn0011656
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001102772.1
• Gene: Srf / 501099
• RGDID: 1559787
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 387
• Identity: 91/387 - (23%)
• Similarity: 155/387 - (40%)
• Gaps: 98/387 - (25%)

  Fly     2 GRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRVL 66
            ||.||::..|.::..|..||:|||.|:||||||||.|...::.|::.|.:..:|.:|:..:..::
  Rat   138 GRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMI 202

  Fly    67 LKYTEYNEPHESLTNKNIIEKENKNGVMSPDSPEAETDYTLTPRTEAKYNKIDEEFQNMMQRNQM 131
                      .|.|.|.:|:    ..:.|||||...     .|.|:.:.:....|..::..:...
  Rat   203 ----------TSETGKALIQ----TCLNSPDSPPRS-----DPSTDQRMSATGFEEPDLTYQVSE 248

  Fly   132 AIGGAGAPRQLPNSSYTLPVSVPVPGSYGDNLLQASPQMSHT-NISPRPSSSETD-------SVY 188
            : ..:|..:.....::|:   ..:||:  .:.:|.:|..|.| .:|..||...|:       ||.
  Rat   249 S-DSSGETKDTLKPAFTV---TNLPGT--TSTIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVS 307

  Fly   189 PS------GSMLEMSNGYPHSHSPLVGSPS-----PG-------PSPGIAHHLSIKQQSPGSQNG 235
            ||      |::|:.:...|.|...|:..|:     ||       |...|..|.:.:|.||...:.
  Rat   308 PSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVAQQVPVQAIHVHQAPQQASPSRDSS 372

  Fly   236 -----RASNLRVVIPPTI--APIPPNMS------APDDVGYA----------------------- 264
                 .:|:..|.:|.||  :.:|..:.      :|..|.||
  Rat   373 TDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLADGSLTVLNAFSQAPSTM 437

  Fly   265 ----DQRQS-----QTSLNTPVVTLQTPIPALTSYSFG--AQDFSSSGVMNSADIMSLNTWH 315
                .|.|.     |..|..|..|:|.|:.|:..:...  .|...||..:....:::|:..|
  Rat   438 QVSHSQVQEPGGVPQVFLTAPSGTVQIPVSAVQLHQMAVIGQQAGSSSNLTELQVVNLDATH 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	ARG80	1..>203	CDD:227400	56/214 (26%)
		MADS_MEF2_like	2..78	CDD:238165	25/75 (33%)
Srf	NP_001102772.1	MADS_SRF_like	138..219	CDD:238166	30/94 (32%)