Protein Alignment Mef2 and mef2d

DIOPT Version :9

• Sequence 1: NP_001260842.1
• Gene: Mef2 / 36032
• FlyBaseID: FBgn0011656
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_571392.1
• Gene: mef2d / 30580
• ZFINID: ZDB-GENE-990415-164
• Length: 529
• Species: Danio rerio
• Alignment Length: 609
• Identity: 208/609 - (34%)
• Similarity: 275/609 - (45%)
• Gaps: 180/609 - (29%)

  Fly     1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRV 65
            ||||||||.||||||||||||.|||||:||||||||||||||||||||:.||||:||||||||:|
Zfish     1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKV 65

  Fly    66 LLKYTEYNEPHESLTNKNIIEKENKNGVMSPDSPEAETDYTLTPRTEAKYNKIDEEFQNMMQRNQ 130
            |||||||||||||.||.:|||..||......:||:.|..::||||||.||.||||||..|||..:
Zfish    66 LLKYTEYNEPHESRTNADIIEALNKKEHRDSESPDPEEPFSLTPRTEEKYKKIDEEFDKMMQSYR 130

  Fly   131 MAIGGAGAPRQLPNSSYTLPVSVPV------PGSYGDNLLQAS----------------PQMSHT 173
            ::       ..:|..::::||:|||      |.|...:|:..|                ||:...
Zfish   131 LS-------STVPAPTFSMPVTVPVSNQSPLPFSNPSSLVTTSFVTSTLTDPRLLSPQQPQLQRN 188

  Fly   174 NISP----RPSS---------SETDSVYPSGSMLEMSNGYPHSH-SPLVGSPSPGPSPGIAHHLS 224
            .:||    ||:|         :.::...||    .::|||..:. ||.:.|.|.|.|.|..  :.
Zfish   189 TVSPGLPQRPASAGALLGGDLNNSNGACPS----PVANGYVSARASPGLLSVSNGNSMGKV--VQ 247

  Fly   225 IKQQSPGS---QNGRASNLRVVIPPTIAPIPPNMSAPDD----VGYADQR----QSQTSLNTPVV 278
            .|...|.|   .|.|..:|||:...:...:   |...|:    |....||    |....|.||||
Zfish   248 AKSPPPPSTQMANSRKPDLRVITSQSSKGL---MQLTDEELELVSENAQRLGTSQVTQPLTTPVV 309

  Fly   279 TLQTPIPALTSYSFGAQDFSSSGVMNSADIMSL--------------NTWHQGLVPH-------- 321
            ::.|| ..||.:|.... :::...:.|||:.:|              .||.|...|.
Zfish   310 SVATP-SLLTPFSMPTA-YNTEYQLTSADLTALQAFTPSGALLPGNMTTWQQQQQPSVSQQPQQQ 372

  Fly   322 -----------------------SSLSHLAVSNSTPPPATSPV----SIKVKAEPQSPPRDLSAS 359
                                   :|||:|....:.|..||..|    ||.:|:||.||.||
Zfish   373 PSVSQQQTQQQQQQQQQPQQLTLASLSNLVPVGTIPHGATLTVNTNPSISIKSEPVSPNRD---- 433

  Fly   360 GHQQNSNGSTGSGGSSSSTSSNASGGAGGGGAVSAANVITHLNNVSVLAGGPSGQGGGGGGGGSN 424
                            .||.|:..|..||   ||...|..:...:.:   .|:|:
Zfish   434 ----------------RSTPSSTPGAVGG---VSGLTVSQYPGTLRL---EPTGR---------- 466

  Fly   425 GNVEQ-ATNLSVLSHAQQHHLGMPNSRP---SSTGHITPTPGAPSSDQDVRLAAVAVQQQQQQPH 485
            ..|:. ::|.|....:.:...|.|  ||   ||.|.:..|...|:             |.:||
Zfish   467 SPVDSISSNGSSYEGSDRDDSGQP--RPPDFSSLGLLRATGDQPA-------------QAEQQ-- 514

  Fly   486 QQQQLGDYDAPNHKRPRISGGWGT 509
                    ::.|.||.|:. .|.|
Zfish   515 --------ESANVKRMRLD-TWVT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	MADS_MEF2_like	2..78	CDD:238165	68/75 (91%)
		HJURP_C	95..155	CDD:289143	24/59 (41%)
mef2d	NP_571392.1	MADS_MEF2_like	2..78	CDD:238165	68/75 (91%)
		HJURP_C	96..152	CDD:289143	26/62 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I7654
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	245	1.000	Inparanoid score	I3261
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D320201at33208
OrthoFinder	1	1.000	-	-		FOG0000108
OrthoInspector	1	1.000	-	-		otm24702
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11945
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1041
SonicParanoid	1	1.000	-	-		X116
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	10.100