Protein Alignment Mef2 and Mef2b

DIOPT Version :9

• Sequence 1: NP_001260842.1
• Gene: Mef2 / 36032
• FlyBaseID: FBgn0011656
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001038949.1
• Gene: Mef2b / 17259
• MGIID: 104526
• Length: 339
• Species: Mus musculus
• Alignment Length: 412
• Identity: 136/412 - (33%)
• Similarity: 184/412 - (44%)
• Gaps: 131/412 - (31%)

  Fly     1 MGRKKIQISRITDERNRQVTFNKRKFGVMKKAYELSVLCDCEIALIIFSSSNKLYQYASTDMDRV 65
            |||||||||||.|:|||||||.|||||:|||||||||||||:||||||:|:.:|:||||:|||||
Mouse     1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRV 65

  Fly    66 LLKYTEYNEPHESLTNKNIIEKENKNGVMSPDSPEAETDYTLTPRTEAKYNKIDEEFQNMMQRNQ 130
            |||||||:|||||.||.:|::...:.|| ..|.||.:               ::|..:...::..
Mouse    66 LLKYTEYSEPHESRTNADILQTLKRRGV-GLDGPELD---------------MEEGPEGPGEKLL 114

  Fly   131 MAIGG-----AGAPRQLP--------NSSYTLPVSVP--VPGSYGDNLLQASPQMSHTNISPRPS 180
            ..:||     :..||..|        ..||.:|.:.|  .||..|:     :|     ::..||
Mouse   115 RTLGGDRGSASPPPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGE-----AP-----SVHSRP- 168

  Fly   181 SSETDSVYPSGSMLEMSNGYPHSHSPLVGSPSPGPSPGIAHHLSIKQQSP--GSQNGRASNLRVV 243
                                ||...|.:|.|...||     ||:.|...|  .:.:||..:|
Mouse   169 --------------------PHFRPPGLGHPIFSPS-----HLASKTPPPLYLATDGRRPDL--- 205

  Fly   244 IPPTIAPIPPNMSAPDDVGYADQRQSQTSLNTPVVTLQTPIPALTSYSF---GAQDFSSSGVMNS 305
                    ||.:           |...:.|.:|    ..|.|||.|::|   |:.|.|.......
Mouse   206 --------PPGL-----------RSLYSGLQSP----GAPGPALGSFAFLPSGSTDCSPGDAAQG 247

  Fly   306 ADIMSLNTW---HQGLVPHSSLSHLAVSNSTPP-----PATSPVSIK------------------ 344
            .  :..:.|   ...:.|...::. ::....||     |.|.|||||
Mouse   248 P--LQPSPWPPTRDAVDPARPVAR-SLCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSF 309

  Fly   345 ----VKAEPQSPPRDLSASGHQ 362
                :.|.|.:.|...|||.|:
Mouse   310 PYPLLLARPLAEPLRPSASLHR 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mef2	NP_001260842.1	MADS_MEF2_like	2..78	CDD:238165	63/75 (84%)
		HJURP_C	95..155	CDD:289143	13/74 (18%)
Mef2b	NP_001038949.1	ARG80	1..>215	CDD:227400	107/287 (37%)
		MADS_MEF2_like	2..78	CDD:238165	63/75 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000108
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X116
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010